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Jacobo-Molina A

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Publications:

Title Authors Year Journal
Major subdomain rearrangement in HIV-1 reverse transcriptase simulated by molecular dynamics. Jacobo-Molina A 1999 Proteins
Structure and functional implications of the polymerase active site region in a complex of HIV-1 RT with a double-stranded DNA template-primer and an antibody Fab fragment at 2.8 A resolution. Jacobo-Molina A 1998 Journal of molecular biology
Insights into DNA polymerization mechanisms from structure and function analysis of HIV-1 reverse transcriptase. Jacobo-Molina A 1995 Biochemistry
Structure of HIV-1 reverse transcriptase in a complex with the non-nucleoside inhibitor alpha-APA R 95845 at 2.8 A resolution. Jacobo-Molina A 1995 Structure (London, England : 1993)
Crystallization of human immunodeficiency virus type 1 reverse transcriptase with and without nucleic acid substrates, inhibitors, and an antibody Fab fragment. Jacobo-Molina A 1995 Methods in enzymology
Sensitivity of wild-type human immunodeficiency virus type 1 reverse transcriptase to dideoxynucleotides depends on template length; the sensitivity of drug-resistant mutants does not. Jacobo-Molina A 1994 Proceedings of the National Academy of Sciences of the United States of America
Locations of anti-AIDS drug binding sites and resistance mutations in the three-dimensional structure of HIV-1 reverse transcriptase. Implications for mechanisms of drug inhibition and resistance. Jacobo-Molina A 1994 Journal of molecular biology
Buried surface analysis of HIV-1 reverse transcriptase p66/p51 heterodimer and its interaction with dsDNA template/primer. Jacobo-Molina A 1994 Journal of molecular recognition : JMR
Crystal structure of human immunodeficiency virus type 1 reverse transcriptase complexed with double-stranded DNA at 3.0 A resolution shows bent DNA. Jacobo-Molina A 1993 Proceedings of the National Academy of Sciences of the United States of America
Structure of HIV-1 reverse transcriptase/DNA complex at 7 A resolution showing active site locations. Jacobo-Molina A 1992 Nature
HIV reverse transcriptase structure-function relationships. Jacobo-Molina A 1991 Biochemistry
Crystals of a ternary complex of human immunodeficiency virus type 1 reverse transcriptase with a monoclonal antibody Fab fragment and double-stranded DNA diffract x-rays to 3.5-A resolution. Jacobo-Molina A 1991 Proceedings of the National Academy of Sciences of the United States of America

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