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Mizushina Y

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Publications:

Title Authors Year Journal
Inhibitory effects of low molecular weight polyphenolics from Inonotus obliquus on human DNA topoisomerase activity and cancer cell proliferation. Mizushina Y 2013 Molecular medicine reports
Cycloartenyl trans-ferulate, a component of the bran byproduct of sake-brewing rice, inhibits mammalian DNA polymerase and suppresses inflammation. Mizushina Y 2013 Food chemistry
Inhibitory effects of myricetin on mammalian DNA polymerase, topoisomerase and human cancer cell proliferation. Mizushina Y 2013 Food chemistry
Inhibition of repair-related DNA polymerases by vitamin Ks, their related quinone derivatives and associated inflammatory activity (Review). Mizushina Y 2013 International journal of oncology
Inhibitory effects of α-mangostin on mammalian DNA polymerase, topoisomerase, and human cancer cell proliferation. Mizushina Y 2013 Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association
Monogalactosyl diacylglycerol, a replicative DNA polymerase inhibitor, from spinach enhances the anti-cell proliferation effect of gemcitabine in human pancreatic cancer cells. Mizushina Y 2012 Biochimica et biophysica acta
Inhibitory effects of glycyrrhetinic Acid on DNA polymerase and inflammatory activities. Mizushina Y 2012 Evidence-based complementary and alternative medicine : eCAM
In vivo antitumor effect of liposomes with sialyl Lewis X including monogalactosyl diacylglycerol, a replicative DNA polymerase inhibitor, from spinach. Mizushina Y 2012 Oncology reports
Inhibitory effects of catechin derivatives on mammalian DNA polymerase and topoisomerase activities and mouse one-cell zygote development. Mizushina Y 2012 Journal of bioscience and bioengineering
Antifungal properties of Japanese cedar essential oil from waste wood chips made from used sake barrels. Mizushina Y 2012 Molecular medicine reports
Effects of Essential Oils from Herbal Plants and Citrus Fruits on DNA Polymerase Inhibitory, Cancer Cell Growth Inhibitory, Antiallergic, and Antioxidant Activities. Mizushina Y 2012 Journal of agricultural and food chemistry
Inhibitory effect of novel somatostatin peptide analogues on human cancer cell growth based on the selective inhibition of DNA polymerase β Mizushina Y 2012 Bioorganic & medicinal chemistry
Inhibitory effects of vitamin K3 derivatives on DNA polymerase and inflammatory activity. Mizushina Y 2011 International journal of molecular medicine
Dehydroaltenusin is a specific inhibitor of mammalian DNA polymerase α Mizushina Y 2011 Expert opinion on investigational drugs
Growth inhibition and chromosomal instability of cultured marsupial (opossum) cells after treatment with DNA polymerase α inhibitor. Mizushina Y 2011 Bioscience, biotechnology, and biochemistry
Acylated catechin derivatives: inhibitors of DNA polymerase and angiogenesis. Mizushina Y 2011 Frontiers in bioscience (Elite edition)
Effects of Intermediates between Vitamins K(2) and K(3) on Mammalian DNA Polymerase Inhibition and Anti-Inflammatory Activity. Mizushina Y 2011 International journal of molecular sciences
Inhibitory effect of novel 5-O-acyl juglones on mammalian DNA polymerase activity, cancer cell growth and inflammatory response. Mizushina Y 2011 Bioorganic & medicinal chemistry
Effects of quinone derivatives, such as 1,4-naphthoquinone, on DNA polymerase inhibition and anti-inflammatory action. Mizushina Y 2011 Medicinal chemistry (Shāriqah (United Arab Emirates))
Anti-cancer effect of spinach glycoglycerolipids as angiogenesis inhibitors based on the selective inhibition of DNA polymerase activity. Mizushina Y 2011 Mini reviews in medicinal chemistry
Consecutive incorporation of fluorophore-labeled nucleotides by mammalian DNA polymerase beta. Mizushina Y 2010 Anal Biochem
Inhibitory effects of sulfobacin B on DNA polymerase and inflammation. Mizushina Y 2010 Int J Mol Med
Inhibitory effects of diacylglyceride phospholipids on DNA polymerase and topoisomerase activities, and human cancer cell growth. Mizushina Y 2010 Medicinal chemistry (Shāriqah (United Arab Emirates))
β-Sitosteryl (6'-O-linoleoyl)-glucoside of soybean (Glycine max L.) crude extract inhibits Y-family DNA polymerases. Mizushina Y 2010 Journal of oleo science
Inhibitory effects of docosyl p-coumarate on DNA topoisomerase activity and human cancer cell growth. Mizushina Y 2010 International journal of oncology
Purified canola lutein selectively inhibits specific isoforms of mammalian DNA polymerases and reduces inflammatory response. Mizushina Y 2010 Lipids
The relationship between the molecular structure of natural acetogenins and their inhibitory activities which affect DNA polymerase, DNA topoisomerase and human cancer cell growth. Mizushina Y 2010 Experimental and therapeutic medicine
Enhancement of human cancer cell radiosensitivity by conjugated eicosapentaenoic acid - a mammalian DNA polymerase inhibitor. Mizushina Y 2010 Int J Oncol
Inhibitory effect of somatostatin Peptide analogues on DNA polymerase activity and human cancer cell proliferation. Mizushina Y 2010 Anticancer Res
Penicilliols A and B, novel inhibitors specific to mammalian Y-family DNA polymerases. Mizushina Y 2009 Bioorganic & medicinal chemistry
Synthesis and DNA polymerase alpha and beta inhibitory activity of alkyl p-coumarates and related compounds. Mizushina Y 2009 Chem Pharm Bull (Tokyo)
Structure and activity relationship of monogalactosyl diacylglycerols, which selectively inhibited in vitro mammalian replicative DNA polymerase activity and human cancer cell growth. Mizushina Y 2009 Cancer Lett
The inhibitory action of kohamaic acid A derivatives on mammalian DNA polymerase beta. Mizushina Y 2009 Molecules
Specific inhibitors of mammalian DNA polymerase species. Mizushina Y 2009 Biosci Biotechnol Biochem
Synthesis and structure-activity relationships of dehydroaltenusin derivatives as selective DNA polymerase alpha inhibitors. Mizushina Y 2009 Bioorg Med Chem
3-O-methylfunicone, a selective inhibitor of mammalian Y-family DNA polymerases from an Australian sea salt fungal strain. Mizushina Y 2009 Marine drugs
Effect of dehydroaltenusin-C12 derivative, a selective DNA polymerase alpha inhibitor, on DNA replication in cultured cells. Mizushina Y 2008 Molecules
Pyranicin, a non-classical annonaceous acetogenin, is a potent inhibitor of DNA polymerase, topoisomerase and human cancer cell growth. Mizushina Y 2008 Int J Oncol
Anti-tumor effect of orally administered spinach glycolipid fraction on implanted cancer cells, colon-26, in mice. Mizushina Y 2008 Lipids
Hymenoic acid, a novel specific inhibitor of human DNA polymerase lambda from a fungus of Hymenochaetaceae sp. Mizushina Y 2008 Bioorg Med Chem
Inhibitory effects of vitamin K3 on DNA polymerase and angiogenesis. Mizushina Y 2008 Int J Mol Med
Novel azaphilones, kasanosins A and B, which are specific inhibitors of eukaryotic DNA polymerases beta and lambda from Talaromyces sp. Mizushina Y 2008 Bioorganic & medicinal chemistry
1-deoxyrubralactone, a novel specific inhibitor of families X and Y of eukaryotic DNA polymerases from a fungal strain derived from sea algae. Mizushina Y 2008 Bioorganic & medicinal chemistry
DNA polymerase gamma inhibition by vitamin K3 induces mitochondria-mediated cytotoxicity in human cancer cells. Mizushina Y 2008 Cancer Sci
Synthetic studies on kohamaic acids: synthesis of structurally simplified analogs of kohamaic acid A. Mizushina Y 2008 Bioscience, biotechnology, and biochemistry
The specific inhibitory effect of demethoxydehydroaltenusin, a derivative of dehydroaltenusin, on mammalian DNA polymerase alpha. Mizushina Y 2008 Int J Mol Med
Inhibitory effects of cholesterol derivatives on DNA polymerase and topoisomerase activities, and human cancer cell growth. Mizushina Y 2008 Lipids
Mechanism of cell cycle arrest and apoptosis induction by conjugated eicosapentaenoic acid, which is a mammalian DNA polymerase and topoisomerase inhibitor. Mizushina Y 2007 International journal of oncology
Anti-tumor effects of dehydroaltenusin, a specific inhibitor of mammalian DNA polymerase alpha. Mizushina Y 2007 Biochem Biophys Res Commun
Epicatechin conjugated with fatty acid is a potent inhibitor of DNA polymerase and angiogenesis. Mizushina Y 2007 Life Sci
Anti-tumor effects of the glycolipids fraction from spinach which inhibited DNA polymerase activity. Mizushina Y 2007 Nutr Cancer
Nodulisporol and Nodulisporone, novel specific inhibitors of human DNA polymerase lambda from a fungus, Nodulisporium sp. Mizushina Y 2007 Bioorg Med Chem
Chemical properties of fatty acid derivatives as inhibitors of DNA polymerases. Mizushina Y 2007 Organic & biomolecular chemistry
Inhibitory effect of coenzyme Q on eukaryotic DNA polymerase gamma and DNA topoisomerase II activities on the growth of a human cancer cell line. Mizushina Y 2006 Cancer Sci
Beta-sitosterol-3-O-beta-D-glucopyranoside: a eukaryotic DNA polymerase lambda inhibitor. Mizushina Y 2006 J Steroid Biochem Mol Biol
Structural relationship of curcumin derivatives binding to the BRCT domain of human DNA polymerase lambda. Mizushina Y 2006 Genes Cells
5-(Hydroxymethyl)-2-furfural: a selective inhibitor of DNA polymerase lambda and terminal deoxynucleotidyltransferase. Mizushina Y 2006 Arch Biochem Biophys
Inhibitory effect of monogalactosyldiacylglycerol, extracted from spinach using supercritical CO2, on mammalian DNA polymerase activity. Mizushina Y 2006 J Agric Food Chem
Inhibitory effect of tocotrienol on eukaryotic DNA polymerase lambda and angiogenesis. Mizushina Y 2006 Biochem Biophys Res Commun
Inhibitory effect of sulfoquinovosyl diacylglycerol on prokaryotic DNA polymerase I activity and cell growth of Escherichia coli. Mizushina Y 2006 J Oleo Sci
Site-directed mutational analysis of structural interactions of low molecule compounds binding to the N-terminal 8 kDa domain of DNA polymerase beta. Mizushina Y 2006 Biochem Biophys Res Commun
Catechin conjugated with fatty acid inhibits DNA polymerase and angiogenesis. Mizushina Y 2006 DNA Cell Biol
Inhibitory effect of mispyric acid on mammalian DNA polymerases. Mizushina Y 2005 Bioscience, biotechnology, and biochemistry
Inhibitory effect of dipeptide alcohol derivatives containing mercapto group on eukaryotic DNA polymerase alpha. Mizushina Y 2005 International journal of molecular medicine
Systematic synthesis of galloyl-substituted procyanidin B1 and B2, and their ability of DPPH radical scavenging activity and inhibitory activity of DNA polymerases. Mizushina Y 2005 Bioorganic & medicinal chemistry
Inhibitory effect of conjugated eicosapentaenoic acid on mammalian DNA polymerase and topoisomerase activities and human cancer cell proliferation. Mizushina Y 2005 Biochem Pharmacol
Structural analysis of isosteviol and related compounds as DNA polymerase and DNA topoisomerase inhibitors. Mizushina Y 2005 Life Sci
Sulfo-quinovosyl-acyl-glycerol (SQAG), a eukaryotic DNA polymerase inhibitor and anti-cancer agent. Mizushina Y 2005 Curr Med Chem Anticancer Agents
Monoacetylcurcumin: a new inhibitor of eukaryotic DNA polymerase lambda and a new ligand for inhibitor-affinity chromatography. Mizushina Y 2005 Biochem Biophys Res Commun
Sulfoquinovosylmonoacylglycerol inhibitory mode analysis of rat DNA polymerase beta. Mizushina Y 2005 FEBS J
Inhibitory effects of glycolipids fraction from spinach on mammalian DNA polymerase activity and human cancer cell proliferation. Mizushina Y 2005 J Nutr Biochem
Structural analysis of catechin derivatives as mammalian DNA polymerase inhibitors. Mizushina Y 2005 Biochem Biophys Res Commun
Structural analysis of epolactaene derivatives as DNA polymerase inhibitors and anti-inflammatory compounds. Mizushina Y 2005 Int J Mol Med
Dipeptide alcohol-based inhibitors of eukaryotic DNA polymerase alpha. Mizushina Y 2005 Bioorg Med Chem
Effects of DNA polymerase inhibitory and antitumor activities of lipase-hydrolyzed glycolipid fractions from spinach. Mizushina Y 2005 J Nutr Biochem
A novel DNA topoisomerase inhibitor: dehydroebriconic acid, one of the lanostane-type triterpene acids from Poria cocos. Mizushina Y 2004 Cancer science
Mechanism of cell cycle arrest by sulfoquinovosyl monoacylglycerol with a C18-saturated fatty acid (C18-SQMG). Mizushina Y 2004 Biochemical pharmacology
Precise structural elucidation of dehydroaltenusin, a specific inhibitor of mammalian DNA polymerase alpha. Mizushina Y 2004 Bioorg Med Chem
Petasiphenol which inhibits DNA polymerase lambda activity is an inhibitor of in vitro angiogenesis. Mizushina Y 2004 Oncol Rep
The effects of dehydroaltenusin, a novel mammalian DNA polymerase alpha inhibitor, on cell proliferation and cell cycle progression. Mizushina Y 2004 Biochimica et biophysica acta
L-Homoserylaminoethanol, a novel dipeptide alcohol inhibitor of eukaryotic DNA polymerase from a plant cultured cells, Nicotina tabacum L. Mizushina Y 2004 Bioorg Med Chem
Dehydrotrametenonic acid and dehydroeburiconic acid from Poria cocos and their inhibitory effects on eukaryotic DNA polymerase alpha and beta. Mizushina Y 2004 Biosci Biotechnol Biochem
Structural relationship of lithocholic acid derivatives binding to the N-terminal 8-kDa domain of DNA polymerase beta. Mizushina Y 2004 Biochemistry
Structure-activity relationships of epolactaene analogs as DNA polymerases inhibitors. Mizushina Y 2004 Bioorganic & medicinal chemistry
Selective inhibition of mammalian DNA polymerase alpha by vitamin D2 and D3. Mizushina Y 2003 J Pharmacol Sci
A sulphoquinovosyl diacylglycerol is a DNA polymerase epsilon inhibitor. Mizushina Y 2003 Biochem J
Molecular action mode of Hippospongic acid A, an inhibitor of gastrulation of starfish embryos. Mizushina Y 2003 Journal of biochemistry
The inhibitory action of pyrrolidine alkaloid, 1,4-dideoxy-1,4-imino-D-ribitol, on eukaryotic DNA polymerases. Mizushina Y 2003 Biochemical and biophysical research communications
Inhibition of DNA polymerases and DNA topoisomerase II by triterpenes produced by plant callus. Mizushina Y 2003 Biochemical and biophysical research communications
Analysis of cell cycle regulation by 1-mono-O-acyl-3-O-(alpha-D-sulfoquinovosyl)-glyceride (SQMG), an inhibitor of eukaryotic DNA polymerases. Mizushina Y 2003 Biochemical pharmacology
Inhibitory action of emulsified sulfoquinovosyl acylglycerol on mammalian DNA polymerases. Mizushina Y 2003 Lipids
Some anti-chronic inflammatory compounds are DNA polymerase lambda-specific inhibitors. Mizushina Y 2003 Biochem Pharmacol
Flavonoid glycoside: a new inhibitor of eukaryotic DNA polymerase alpha and a new carrier for inhibitor-affinity chromatography. Mizushina Y 2003 Biochem Biophys Res Commun
A novel DNA polymerase inhibitor and a potent apoptosis inducer: 2-mono-O-acyl-3-O-(alpha-D-sulfoquinovosyl)-glyceride with stearic acid. Mizushina Y 2003 Biochimica et biophysica acta
Effects of glycolipids from spinach on mammalian DNA polymerases. Mizushina Y 2003 Biochemical pharmacology
Inhibitory effect of pyridoxal 5'-phosphate on endothelial cell proliferation, replicative DNA polymerase and DNA topoisomerase. Mizushina Y 2003 Int J Mol Med
Pyridoxal 5'-phosphate is a selective inhibitor in vivo of DNA polymerase alpha and epsilon. Mizushina Y 2003 Biochem Biophys Res Commun
Vitamin A-related compounds, all-trans retinal and retinoic acids, selectively inhibit activities of mammalian replicative DNA polymerases. Mizushina Y 2002 Biochimica et biophysica acta
Structure-function relationship of synthetic sulfoquinovosyl-acylglycerols as mammalian DNA polymerase inhibitors. Mizushina Y 2002 Arch Biochem Biophys
[Structural homology between molecular probes binding site of DNA polymerase beta and DNA topoisomerase II]. Mizushina Y 2002 Tanpakushitsu Kakusan Koso
Actions of derivatives of dehydroaltenusin, a new mammalian DNA polymerase alpha-specific inhibitor. Mizushina Y 2002 Biochem Pharmacol
Selective inhibition of the activities of both eukaryotic DNA polymerases and DNA topoisomerases by elenic acid. Mizushina Y 2002 Biochemical pharmacology
Three-dimensional structural model analysis of the binding site of an inhibitor, nervonic acid, of both DNA polymerase beta and HIV-1 reverse transcriptase. Mizushina Y 2002 Journal of biochemistry
A plant phytotoxin, solanapyrone A, is an inhibitor of DNA polymerase beta and lambda. Mizushina Y 2002 The Journal of biological chemistry
Petasiphenol: a DNA polymerase lambda inhibitor. Mizushina Y 2002 Biochemistry
Novel anti-inflammatory compounds from Rubus sieboldii, triterpenoids, are inhibitors of mammalian DNA polymerases. Mizushina Y 2002 Biochimica et biophysica acta
Specific interaction between an oligosaccharide on the tumor cell surface and the novel antitumor agents, sulfoquinovosylacylglycerols. Mizushina Y 2001 Biochemical and biophysical research communications
Three-dimensional structural model analysis of the binding site of lithocholic acid, an inhibitor of DNA polymerase beta and DNA topoisomerase II. Mizushina Y 2001 J Biochem
Synthesis of sulfoquinovosylacylglycerols, inhibitors of eukaryotic DNA polymerase alpha and beta. Mizushina Y 2001 Bioorg Med Chem
Galactosyldiacylglycerol, a mammalian DNA polymerase alpha-specific inhibitor from a sea alga, Petalonia bingbamiae. Mizushina Y 2001 Biol Pharm Bull
Mode analysis of binding of fatty acids to mammalian DNA polymerases. Mizushina Y 2000 Biochimica et biophysica acta
Structural homology between DNA binding sites of DNA polymerase beta and DNA topoisomerase II. Mizushina Y 2000 Journal of molecular biology
Novel triterpenoids inhibit both DNA polymerase and DNA topoisomerase. Mizushina Y 2000 Biochem J
Studies on a novel DNA polymerase inhibitor group, synthetic sulfoquinovosylacylglycerols: inhibitory action on cell proliferation. Mizushina Y 2000 Mutation research
Structure-activity relationship of a novel group of mammalian DNA polymerase inhibitors, synthetic sulfoquinovosylacylglycerols. Mizushina Y 2000 Jpn J Cancer Res
Structure of lithocholic acid binding to the N-terminal 8-kDa domain of DNA polymerase beta. Mizushina Y 2000 Biochemistry
Differentiation of rat pheochromocytoma cells by fomitellic acids, specific DNA polymerase inhibitors. Mizushina Y 2000 Life Sci
Dehydroaltenusin, a mammalian DNA polymerase alpha inhibitor. Mizushina Y 2000 The Journal of biological chemistry
Novel anti-inflammatory compounds from Myrsine seguinii, terpeno-benzoic acids, are inhibitors of mammalian DNA polymerases. Mizushina Y 2000 Biochimica et biophysica acta
Epolactaene, a novel neuritogenic compound in human neuroblastoma cells, selectively inhibits the activities of mammalian DNA polymerases and human DNA topoisomerase II. Mizushina Y 2000 Biochemical and biophysical research communications
The biochemical mode of inhibition of DNA polymerase beta by alpha-rubromycin. Mizushina Y 2000 Biochimica et biophysica acta
Mode analysis of a fatty acid molecule binding to the N-terminal 8-kDa domain of DNA polymerase beta. A 1:1 complex and binding surface. Mizushina Y 1999 The Journal of biological chemistry
The cyanogenic glucoside, prunasin (D-mandelonitrile-beta-D-glucoside), is a novel inhibitor of DNA polymerase beta. Mizushina Y 1999 J Biochem
Action of a new mammalian DNA polymerase inhibitor, sulfoquinovosyldiacylglycerol. Mizushina Y 1999 Biol Pharm Bull
Lucidenic acid O and lactone, new terpene inhibitors of eukaryotic DNA polymerases from a basidiomycete, Ganoderma lucidum. Mizushina Y 1999 Bioorganic & medicinal chemistry
The biochemical inhibition mode of bredinin-5'-monophosphate on DNA polymerase beta. Mizushina Y 1998 Biochimica et biophysica acta
Purification and characterization of a 100 kDa DNA polymerase from cauliflower inflorescence. Mizushina Y 1998 Biochem J
An ergosterol peroxide, a natural product that selectively enhances the inhibitory effect of linoleic acid on DNA polymerase beta. Mizushina Y 1998 Biol Pharm Bull
A 5'-monophosphate form of bredinin selectively inhibits the activities of mammalian DNA polymerases in vitro. Mizushina Y 1998 International journal of molecular medicine
Carboxyflavins, novel inhibitors of Taq DNA polymerase. Mizushina Y 1998 International journal of molecular medicine
A mushroom fruiting body-inducing substance inhibits activities of replicative DNA polymerases. Mizushina Y 1998 Biochemical and biophysical research communications
4-Hydroxy-17-methylincisterol, an inhibitor of DNA polymerase-alpha activity and the growth of human cancer cells in vitro. Mizushina Y 1998 Biochemical pharmacology
Fomitellic acids, triterpenoid inhibitors of eukaryotic DNA polymerases from a basidiomycete, Fomitella fraxinea. Mizushina Y 1998 Journal of natural products
Studies on inhibitors of mammalian DNA polymerase alpha and beta: sulfolipids from a pteridophyte, Athyrium niponicum. Mizushina Y 1998 Biochemical pharmacology
The inhibitory effect of novel triterpenoid compounds, fomitellic acids, on DNA polymerase beta. Mizushina Y 1998 Biochem J
Sulfoquinovosyldiacylglycerol, KM043, a new potent inhibitor of eukaryotic DNA polymerases and HIV-reverse transcriptase type 1 from a marine red alga, Gigartina tenella. Mizushina Y 1998 Chemical & pharmaceutical bulletin
The inhibitory action of fatty acids on DNA polymerase beta. Mizushina Y 1997 Biochimica et biophysica acta
Fatty acids selectively inhibit eukaryotic DNA polymerase activities in vitro. Mizushina Y 1996 Biochimica et biophysica acta

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