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Lloyd RS

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Publications:

Title Authors Year Journal
Translesion synthesis past acrolein-derived DNA adducts by human mitochondrial DNA polymerase γ Lloyd RS 2013 The Journal of biological chemistry
Ring-opening of the γ-OH-PdG adduct promotes error-free bypass by the Sulfolobus solfataricus DNA polymerase Dpo4. Lloyd RS 2013 Chemical research in toxicology
Inhibition of HIV-1 Reverse Transcriptase-Catalyzed Synthesis by Intercalated DNA Benzo[a]Pyrene 7,8-Dihydrodiol-9,10-Epoxide Adducts. Lloyd RS 2013 PloS one
Leukotriene biosynthesis inhibitor MK886 impedes DNA polymerase activity. Lloyd RS 2013 Chemical research in toxicology
A comprehensive strategy to discover inhibitors of the translesion synthesis DNA polymerase κ. Lloyd RS 2012 PloS one
DNA Polymerase β Gap-filling Translesion DNA Synthesis. Lloyd RS 2012 Chemical research in toxicology
Role of high-fidelity Escherichia coli DNA polymerase I in replication bypass of a deoxyadenosine DNA-peptide cross-link. Lloyd RS 2011 Journal of bacteriology
Novel enzymatic function of DNA polymerase nu in translesion DNA synthesis past major groove DNA-peptide and DNA-DNA cross-links. Lloyd RS 2010 Chemical research in toxicology
Replication bypass of interstrand cross-link intermediates by Escherichia coli DNA polymerase IV. Lloyd RS 2008 The Journal of biological chemistry
Replication bypass of the acrolein-mediated deoxyguanine DNA-peptide cross-links by DNA polymerases of the DinB family. Lloyd RS 2008 Chemical research in toxicology
Role for DNA polymerase kappa in the processing of N2-N2-guanine interstrand cross-links. Lloyd RS 2008 The Journal of biological chemistry
Replication past a trans-4-hydroxynonenal minor-groove adduct by the sequential action of human DNA polymerases iota and kappa. Lloyd RS 2006 Molecular and cellular biology
Human DNA polymerase iota promotes replication through a ring-closed minor-groove adduct that adopts a syn conformation in DNA. Lloyd RS 2005 Molecular and cellular biology
Efficient and error-free replication past a minor-groove DNA adduct by the sequential action of human DNA polymerases iota and kappa. Lloyd RS 2004 Molecular and cellular biology
Efficient and error-free replication past a minor-groove N2-guanine adduct by the sequential action of yeast Rev1 and DNA polymerase zeta. Lloyd RS 2004 Molecular and cellular biology
Translesion synthesis past acrolein-derived DNA adduct, gamma -hydroxypropanodeoxyguanosine, by yeast and human DNA polymerase eta. Lloyd RS 2003 The Journal of biological chemistry
Translesion DNA synthesis by yeast DNA polymerase eta on templates containing N2-guanine adducts of 1,3-butadiene metabolites. Lloyd RS 2001 The Journal of biological chemistry
Vertical-scanning mutagenesis of a critical tryptophan in the "minor groove binding track" of HIV-1 reverse transcriptase. Major groove DNA adducts identify specific protein interactions in the minor groove. Lloyd RS 2000 The Journal of biological chemistry
Lack of correlation between in vitro and in vivo replication of precisely defined benz-a-anthracene adducted DNAs. Lloyd RS 1997 The Journal of biological chemistry
Probing structure/function relationships of HIV-1 reverse transcriptase with styrene oxide N2-guanine adducts. Lloyd RS 1997 The Journal of biological chemistry
Evidence for an imino intermediate in the DNA polymerase beta deoxyribose phosphate excision reaction. Lloyd RS 1996 The Journal of biological chemistry
In vitro replication by prokaryotic and eukaryotic polymerases on DNA templates containing site-specific and stereospecific benzo[a]pyrene-7,8-dihydrodiol-9,10-epoxide adducts. Lloyd RS 1995 Nucleic acids research

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