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Desmyter J

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Publications:

Title Authors Year Journal
Prevalence of genotypic resistance among antiretroviral drug-naive HIV-1-infected patients in Belgium. Desmyter J 2001 Antiviral therapy
Presence of 2',5'-Bis-O-(tert-butyldimethylsilyl)-3'-spiro-5"-(4"-amino-1",2"-oxath iole-2",2"-dioxide) (TSAO)-resistant virus strains in TSAO-inexperienced HIV patients. Desmyter J 2000 AIDS research and human retroviruses
In vitro evaluation of the effect of temporary removal of HIV drug pressure. Desmyter J 2000 Antiviral research
Evaluating Clinical Isolates for Their Phenotypic and Genotypic Resistance Against Anti-HIV Drugs. Desmyter J 2000 Methods in molecular medicine
Activity of non-nucleoside reverse transcriptase inhibitors against HIV-2 and SIV. Desmyter J 1999 AIDS (London, England)
1,1,3-Trioxo-2H,4H-thieno[3,4-e][1,2,4]thiadiazine (TTD) derivatives: a new class of nonnucleoside human immunodeficiency virus type 1 (HIV-1) reverse transcriptase inhibitors with anti-HIV-1 activity. Desmyter J 1998 Antimicrobial agents and chemotherapy
Comparison of the LiPA HIV-1 RT test, selective PCR and direct solid phase sequencing for the detection of HIV-1 drug resistance mutations. Desmyter J 1998 Journal of virological methods
Multiple dideoxynucleoside analogue-resistant (MddNR) HIV-1 strains isolated from patients from different European countries. Desmyter J 1998 AIDS (London, England)
SRR-SB3, a disulfide-containing macrolide that inhibits a late stage of the replicative cycle of human immunodeficiency virus. Desmyter J 1997 Antimicrobial agents and chemotherapy
New arylpyrido-diazepine and -thiodiazepine derivatives are potent and highly selective HIV-1 inhibitors targeted at the reverse transcriptase. Desmyter J 1996 Antiviral research
Antiviral activity of the bicyclam derivative JM3100 against drug-resistant strains of human immunodeficiency virus type 1. Desmyter J 1996 Antiviral research
A two plasmid co-expression system in Escherichia coli for the production of virion-like reverse transcriptase of the human immunodeficiency virus type 1. Desmyter J 1996 Journal of virological methods
New tetrahydroimidazo[4,5,1-jk][1,4]-benzodiazepin-2(1H)-one and -thione derivatives are potent inhibitors of human immunodeficiency virus type 1 replication and are synergistic with 2',3'-dideoxynucleoside analogs. Desmyter J 1994 Antimicrobial agents and chemotherapy
Resistance of HIV-1 reverse transcriptase against [2',5'-bis-O-(tert-butyldimethylsilyl)-3'-spiro-5''-(4''-amino-1'',2''- oxathiole-2'',2''-dioxide)] (TSAO) derivatives is determined by the mutation Glu138-->Lys on the p51 subunit. Desmyter J 1994 The Journal of biological chemistry
Kinetics of different human immunodeficiency virus type 1 reverse transcriptases resistant to human immunodeficiency virus type 1-specific reverse transcriptase inhibitors. Desmyter J 1993 Molecular pharmacology
Inhibition of visna virus replication by 2',3'-dideoxynucleosides and acyclic nucleoside phosphonate analogs. Desmyter J 1993 Antimicrobial agents and chemotherapy
Allosteric inhibition of human immunodeficiency virus type 1 reverse transcriptase by tetrahydroimidazo[4,5,1-jk][1,4]benzodiazepin-2(1H)-one and -thione compounds. Desmyter J 1992 Molecular pharmacology
Resistance of human immunodeficiency virus type 1 reverse transcriptase to TIBO derivatives induced by site-directed mutagenesis. Desmyter J 1992 Virology
Common features in the interaction of tetrahydroimidazo[4,5,1-jk][1,4]benzodiazepin-2(1H)-one and -thione and 1-[(2-hydroxyethoxy)methyl]-6-(phenylthio)thymine derivatives with the human immunodeficiency virus type 1 reverse transcriptase. Desmyter J 1992 Molecular pharmacology
Differential inhibitory effects of TIBO derivatives on different strains of simian immunodeficiency virus. Desmyter J 1992 The Journal of general virology
Kinetics of inhibition of endogenous human immunodeficiency virus type 1 reverse transcription by 2',3'-dideoxynucleoside 5'-triphosphate, tetrahydroimidazo-[4,5,1-jk][1,4]-benzodiazepin-2(1H)-thion e, and 1-[(2-hydroxyethoxy)methyl]-6-(phenylthio)thymine derivatives. Desmyter J 1992 The Journal of biological chemistry
An antiviral target on reverse transcriptase of human immunodeficiency virus type 1 revealed by tetrahydroimidazo-[4,5,1-jk] [1,4]benzodiazepin-2 (1H)-one and -thione derivatives. Desmyter J 1991 Proceedings of the National Academy of Sciences of the United States of America
Mechanism of inhibitory effect of dextran sulfate and heparin on replication of human immunodeficiency virus in vitro. Desmyter J 1988 Proceedings of the National Academy of Sciences of the United States of America

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