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Ohta K

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Publications:

Title Authors Year Journal
A sulfoglycolipid beta-sulfoquinovosyldiacylglycerol (betaSQDG) binds to Met1-Arg95 region of murine DNA polymerase lambda (Mmpol lambda) and inhibits its nuclear transit. Ohta K 2010 Protein Eng Des Sel
Site-directed mutational analysis of structural interactions of low molecule compounds binding to the N-terminal 8 kDa domain of DNA polymerase beta. Ohta K 2006 Biochem Biophys Res Commun
Mammalian mitotic centromere-associated kinesin (MCAK): a new molecular target of sulfoquinovosylacylglycerols novel antitumor and immunosuppressive agents. Ohta K 2005 The FEBS journal
Effective form of sulfoquinovosyldiacyglycerol (SQDG) vesicles for DNA polymerase inhibition. Ohta K 2005 Colloids Surf B Biointerfaces
Molecular design of cholesterols as inhibitors of DNA polymerase alpha. Ohta K 2004 J Med Chem
A novel DNA polymerase inhibitor and a potent apoptosis inducer: 2-mono-O-acyl-3-O-(alpha-D-sulfoquinovosyl)-glyceride with stearic acid. Ohta K 2003 Biochimica et biophysica acta
Structure-function relationship of synthetic sulfoquinovosyl-acylglycerols as mammalian DNA polymerase inhibitors. Ohta K 2002 Arch Biochem Biophys
Actions of derivatives of dehydroaltenusin, a new mammalian DNA polymerase alpha-specific inhibitor. Ohta K 2002 Biochem Pharmacol
Selective inhibition of the activities of both eukaryotic DNA polymerases and DNA topoisomerases by elenic acid. Ohta K 2002 Biochemical pharmacology
Specific interaction between an oligosaccharide on the tumor cell surface and the novel antitumor agents, sulfoquinovosylacylglycerols. Ohta K 2001 Biochemical and biophysical research communications
Synthesis of sulfoquinovosylacylglycerols, inhibitors of eukaryotic DNA polymerase alpha and beta. Ohta K 2001 Bioorg Med Chem
Galactosyldiacylglycerol, a mammalian DNA polymerase alpha-specific inhibitor from a sea alga, Petalonia bingbamiae. Ohta K 2001 Biol Pharm Bull
Novel triterpenoids inhibit both DNA polymerase and DNA topoisomerase. Ohta K 2000 Biochem J
Novel anti-inflammatory compounds from Myrsine seguinii, terpeno-benzoic acids, are inhibitors of mammalian DNA polymerases. Ohta K 2000 Biochimica et biophysica acta
Studies on a novel DNA polymerase inhibitor group, synthetic sulfoquinovosylacylglycerols: inhibitory action on cell proliferation. Ohta K 2000 Mutation research
Structure-activity relationship of a novel group of mammalian DNA polymerase inhibitors, synthetic sulfoquinovosylacylglycerols. Ohta K 2000 Jpn J Cancer Res
Action of a new mammalian DNA polymerase inhibitor, sulfoquinovosyldiacylglycerol. Ohta K 1999 Biol Pharm Bull
Studies on inhibitors of mammalian DNA polymerase alpha and beta: sulfolipids from a pteridophyte, Athyrium niponicum. Ohta K 1998 Biochemical pharmacology
Sulfoquinovosyldiacylglycerol, KM043, a new potent inhibitor of eukaryotic DNA polymerases and HIV-reverse transcriptase type 1 from a marine red alga, Gigartina tenella. Ohta K 1998 Chemical & pharmaceutical bulletin
An ergosterol peroxide, a natural product that selectively enhances the inhibitory effect of linoleic acid on DNA polymerase beta. Ohta K 1998 Biol Pharm Bull

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