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Menéndez-Arias L

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Publications:

Title Authors Year Journal
Identification of low-molecular weight inhibitors of HIV-1 reverse transcriptase using a cell-based high-throughput screening system. Menéndez-Arias L 2011 Antiviral research
Effect of the human immunodeficiency virus type 1 reverse transcriptase polymorphism Leu-214 on replication capacity and drug susceptibility. Menéndez-Arias L 2009 Journal of virology
Mutation Rates and Intrinsic Fidelity of Retroviral Reverse Transcriptases Menéndez-Arias L 2009 Viruses
Mutational patterns associated with the 69 insertion complex in multi-drug-resistant HIV-1 reverse transcriptase that confer increased excision activity and high-level resistance to zidovudine. Menéndez-Arias L 2007 Journal of molecular biology
Multidrug-resistant HIV-1 reverse transcriptase: involvement of ribonucleotide-dependent phosphorolysis in cross-resistance to nucleoside analogue inhibitors. Menéndez-Arias L 2002 Journal of molecular biology
Molecular basis of fidelity of DNA synthesis and nucleotide specificity of retroviral reverse transcriptases. Menéndez-Arias L 2002 Prog Nucleic Acid Res Mol Biol
Functional characterization of chimeric reverse transcriptases with polypeptide subunits of highly divergent HIV-1 group M and O strains. Menéndez-Arias L 2001 The Journal of biological chemistry
A mutation in the primer grip region of HIV-1 reverse transcriptase that confers reduced fidelity of DNA synthesis. Menéndez-Arias L 2001 Nucleic acids research
Investigation of the dNTP-binding site of HIV-1 reverse transcriptase using photoreactive analogs of dNTP. Menéndez-Arias L 2001 Biochemistry. Biokhimii͡a
Coupling ribose selection to fidelity of DNA synthesis. The role of Tyr-115 of human immunodeficiency virus type 1 reverse transcriptase. Menéndez-Arias L 2000 The Journal of biological chemistry
Role of a dipeptide insertion between codons 69 and 70 of HIV-1 reverse transcriptase in the mechanism of AZT resistance. Menéndez-Arias L 2000 The EMBO journal
Human immunodeficiency virus type 1 reverse transcriptase: role of Tyr115 in deoxynucleotide binding and misinsertion fidelity of DNA synthesis. Menéndez-Arias L 1996 The EMBO journal

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