| DNA polymerases I and II in regenerating rat liver and Morris hepatomas. |
Baril EF, Jenkins MD, Brown OE, Laszlo J, Morris HP |
1973 |
| Inhibition of DNA polymerase from L1210 murine leukemia by a sulfhydryl reagent from agaricus bisporus. |
Graham DG, Tye RW, Vogel FS |
1977 |
| Construction of a minimal HIV-1 variant that selectively replicates in leukemic derived T-cell lines: towards a new virotherapy approach. |
Jeeninga RE, Jan B, van der Linden B, van den Berg H, Berkhout B |
2005 |
| Selective response of DNA polymerase beta to bleomycin-induced breaks in DNA. |
Coetzee ML, Chou R, Ove P |
1978 |
| Regulation of DNA polymerase beta by the LMP1 oncoprotein of EBV through the nuclear factor-kappaB pathway. |
Faumont N, Le Clorennec C, Teira P, Goormachtigh G, Coll J, Canitrot Y, Cazaux C, Hoffmann JS, Brousset P, Delsol G, Feuillard J, Meggetto F |
2009 |
| Evaluation of growth fractions with monoclonal antibodies to human alpha-DNA polymerase. |
Alama A, Nicolin A, Conte PF, Drewinko B |
1987 |
| Effects of arsenic, selenium, and chromium on the fidelity of DNA synthesis. |
Tkeshelashvili LK, Shearman CW, Zakour RA, Koplitz RM, Loeb LA |
1980 |
| Elevated DNA polymerase alpha, DNA polymerase beta, and DNA topoisomerase II in a melphalan-resistant rhabdomyosarcoma xenograft that is cross-resistant to nitrosoureas and topotecan. |
Friedman HS, Dolan ME, Kaufmann SH, Colvin OM, Griffith OW, Moschel RC, Schold SC, Bigner DD, Ali-Osman F |
1994 |
| Effects of estrogen and antiestrogen on DNA polymerase in human breast cancer. |
Edwards DP, Murthy SR, McGuire WL |
1980 |
| Recapitulation of the cellular xeroderma pigmentosum-variant phenotypes using short interfering RNA for DNA polymerase H. |
Laposa RR, Feeney L, Cleaver JE |
2003 |
| Modulation of drug resistance mediated by loss of mismatch repair by the DNA polymerase inhibitor aphidicolin. |
Moreland NJ, Illand M, Kim YT, Paul J, Brown R |
1999 |
| Evidence that in xeroderma pigmentosum variant cells, which lack DNA polymerase eta, DNA polymerase iota causes the very high frequency and unique spectrum of UV-induced mutations. |
Wang Y, Woodgate R, McManus TP, Mead S, McCormick JJ, Maher VM |
2007 |
| The effect of divalent nickel (Ni2+) on in vitro DNA replication by DNA polymerase alpha. |
Chin YE, Snow ET, Cohen MD, Christie NT |
1994 |
| DNA polymerase alpha-primase complexes from carcinogen-treated Chinese hamster ovary cells. |
Brucker A, Loeb LA, Thielmann HW |
1990 |
| Effects of 1-beta-D-arabinofuranosylcytosine incorporation on elongation of specific DNA sequences by DNA polymerase beta. |
Ohno Y, Spriggs D, Matsukage A, Ohno T, Kufe D |
1988 |
| A novel nuclear protein, MGC5306 interacts with DNA polymerase beta and has a potential role in cellular phenotype. |
Wang L, Bhattacharyya N, Chelsea DM, Escobar PF, Banerjee S |
2004 |
| Isolation of a DNA polymerase alpha-associated regulatory protein from calf thymus. |
Steinberg JA, Otten M, Grindey GB |
1979 |
| DNA polymerase beta interacts with TRF2 and induces telomere dysfunction in a murine mammary cell line. |
Fotiadou P, Henegariu O, Sweasy JB |
2004 |
| Deregulated DNA polymerase beta induces chromosome instability and tumorigenesis. |
Bergoglio V, Pillaire MJ, Lacroix-Triki M, Raynaud-Messina B, Canitrot Y, Bieth A, Garès M, Wright M, Delsol G, Loeb LA, Cazaux C, Hoffmann JS |
2002 |
| Stimulation of Rauscher leukemia virus DNA polymerase DNA-directed DNA synthesis by cationic trypanocides and polyamines. |
Marcus SL, Petrylak DP, Burchenal JJ, Bacchi CJ |
1985 |
| Targeted radiosensitization of cells expressing truncated DNA polymerase {beta}. |
Neijenhuis S, Verwijs-Janssen M, van den Broek LJ, Begg AC, Vens C |
2010 |
| Telomere repeat binding factor 2 interacts with base excision repair proteins and stimulates DNA synthesis by DNA polymerase beta. |
Muftuoglu M, Wong HK, Imam SZ, Wilson DM, Bohr VA, Opresko PL |
2006 |
| DNA polymerase kappa, implicated in spontaneous and DNA damage-induced mutagenesis, is overexpressed in lung cancer. |
O-Wang J, Kawamura K, Tada Y, Ohmori H, Kimura H, Sakiyama S, Tagawa M |
2001 |
| Substrate specificity of the exonuclease associated with calf DNA polymerase. |
Sabatino RD, Myers TW, Bambara RA |
1990 |
| A role for polymerase eta in the cellular tolerance to cisplatin-induced damage. |
Albertella MR, Green CM, Lehmann AR, O'Connor MJ |
2005 |
| Codons 12 and 13 of H-ras protooncogene interrupt the progression of DNA synthesis catalyzed by DNA polymerase alpha. |
Hoffmann JS, Fry M, Ji J, Williams KJ, Loeb LA |
1993 |
| Up-regulation of the error-prone DNA polymerase {kappa} promotes pleiotropic genetic alterations and tumorigenesis. |
Bavoux C, Leopoldino AM, Bergoglio V, O-Wang J, Ogi T, Bieth A, Judde JG, Pena SD, Poupon MF, Helleday T, Tagawa M, Machado C, Hoffmann JS, Cazaux C |
2005 |
| Analysis of c-Ki-ras mutations in human colon carcinoma by cell sorting, polymerase chain reaction, and DNA sequencing. |
Burmer GC, Rabinovitch PS, Loeb LA |
1989 |
| DNA polymerase beta gene mutation in human prostate cancer. |
Dobashi Y, Shuin T, Tsuruga H, Uemura H, Torigoe S, Kubota Y |
1994 |
| Levodopa and dopamine analogs as DNA polymerase inhibitors and antitumor agents in human melanoma. |
Wick MM |
1980 |
| DNA polymerase beta mutations in human colorectal cancer. |
Wang L, Patel U, Ghosh L, Banerjee S |
1992 |
| Potentiation of temozolomide cytotoxicity by inhibition of DNA polymerase beta is accentuated by BRCA2 mutation. |
Stachelek GC, Dalal S, Donigan KA, Campisi Hegan D, Sweasy JB, Glazer PM |
2010 |
| Inhibition of human DNA polymerase alpha by alpha 1-antichymotrypsin. |
Tsuda M, Masuyama M, Katsunuma T |
1986 |
| Mutation frequencies and spectra in DNA polymerase eta-deficient mice. |
Busuttil RA, Lin Q, Stambrook PJ, Kucherlapati R, Vijg J |
2008 |
| DNA synthesis and DNA polymerase activity in Leydig cells of diethylstilbestrol-stimulated mouse testes. |
Spruance SL, Wilcox B, Richards OC, Foster DN, Huseby RA, Samuels LT |
1978 |
| Loss of DNA polymerase zeta causes chromosomal instability in mammalian cells. |
Wittschieben JP, Reshmi SC, Gollin SM, Wood RD |
2006 |
| Reactive oxygen species in tumorigenesis. |
Feig DI, Reid TM, Loeb LA |
1994 |
| Induction of a low level of microsatellite instability by overexpression of DNA polymerase Beta. |
Yamada NA, Farber RA |
2002 |
| Effect of a template-located 2',2'-difluorodeoxycytidine on the kinetics and fidelity of base insertion by Klenow (3'-->5'exonuclease-) fragment. |
Schy WE, Hertel LW, Kroin JS, Bloom LB, Goodman MF, Richardson FC |
1993 |
| Demonstration of Epstein-Barr virus-specific DNA polymerase in chemically induced Raji cells and its antibody in serum from patients with nasopharyngeal carcinoma. |
Tan RS, Li JS, Grill SP, Nutter LM, Cheng YC |
1986 |
| p53 mutations in non-small cell lung cancer in Japan: association between mutations and smoking. |
Suzuki H, Takahashi T, Kuroishi T, Suyama M, Ariyoshi Y, Takahashi T, Ueda R |
1992 |
| The role of DNA polymerase eta in translesion synthesis past platinum-DNA adducts in human fibroblasts. |
Bassett E, King NM, Bryant MF, Hector S, Pendyala L, Chaney SG, Cordeiro-Stone M |
2004 |
| Additive effects of bleomycin and neocarzinostatin on degradation of DNA, inhibition of DNA polymerase beta, and cell growth. |
Müller WE, Maidhof A, Arendes J, Geurtsen W, Zahn RK, Schmidseder R |
1979 |
| Induction of spleen cell growth and DNA polymerase activity by Corynebacterium parvum. |
Maruyama Y, Coleman MS |
1978 |
| Action of partially thiolated polynucleotides on the DNA polymerase alpha from regenerating rat liver. |
Kung MP, Ho YK, Bardos TJ |
1976 |
| DNA polymerase beta mediates protection of mammalian cells against ganciclovir-induced cytotoxicity and DNA breakage. |
Tomicic MT, Thust R, Sobol RW, Kaina B |
2001 |
| Utilization of 2'-deoxy-6-thioguanosine 5'-triphosphate in DNA synthesis in vitro by DNA polymerase alpha from calf thymus. |
Yoshida S, Yamada M, Masaki S, Saneyoshi M |
1979 |
| Regulation of DNA polymerase POLD4 influences genomic instability in lung cancer. |
Huang QM, Tomida S, Masuda Y, Arima C, Cao K, Kasahara TA, Osada H, Yatabe Y, Akashi T, Kamiya K, Takahashi T, Suzuki M |
2010 |
| Altered sensitivity to 1-beta-D-arabinofuranosylcytosine 5'-triphosphate of DNA polymerase alpha from leukemic blasts of acute lymphoblastic leukemia. |
TAnaka M, Yoshida S |
1982 |
| Loss of DNA polymerase zeta enhances spontaneous tumorigenesis. |
Wittschieben JP, Patil V, Glushets V, Robinson LJ, Kusewitt DF, Wood RD |
2010 |
| Haploinsufficiency in DNA polymerase beta increases cancer risk with age and alters mortality rate. |
Cabelof DC, Ikeno Y, Nyska A, Busuttil RA, Anyangwe N, Vijg J, Matherly LH, Tucker JD, Wilson SH, Richardson A, Heydari AR |
2006 |
| Altered DNA polymerase iota expression in breast cancer cells leads to a reduction in DNA replication fidelity and a higher rate of mutagenesis. |
Yang J, Chen Z, Liu Y, Hickey RJ, Malkas LH |
2004 |
| Deficiency in DNA polymerase beta provokes replication-dependent apoptosis via DNA breakage, Bcl-2 decline and caspase-3/9 activation. |
Ochs K, Lips J, Profittlich S, Kaina B |
2002 |
| Overexpression of DNA polymerase beta sensitizes mammalian cells to 2',3'-deoxycytidine and 3'-azido-3'-deoxythymidine. |
Bouayadi K, Hoffmann JS, Fons P, Tiraby M, Reynes JP, Cazaux C |
1997 |
| Studies on the activity of the A particle-associated Dna polymerase. |
Bohn EW, Wilson SH |
1974 |
| Increased susceptibility to UV-induced skin carcinogenesis in polymerase eta-deficient mice. |
Lin Q, Clark AB, McCulloch SD, Yuan T, Bronson RT, Kunkel TA, Kucherlapati R |
2006 |
| Correction of hypermutability, N-methyl-N'-nitro-N-nitrosoguanidine resistance, and defective DNA mismatch repair by introducing chromosome 2 into human tumor cells with mutations in MSH2 and MSH6. |
Umar A, Koi M, Risinger JI, Glaab WE, Tindall KR, Kolodner RD, Boland CR, Barrett JC, Kunkel TA |
1997 |
| Effect of hyperthermia on the survival of normal human peripheral blood mononuclear cells. |
Agarwal SS, Katz EJ, Loeb LA |
1983 |
| DNA replication of X-irradiated human lymphocytes. |
Agarwal SS, Katz EJ, Krishan A, Loeb LA |
1981 |
| Progesterone regulates human telomerase reverse transcriptase gene expression via activation of mitogen-activated protein kinase signaling pathway. |
Wang Z, Kyo S, Takakura M, Tanaka M, Yatabe N, Maida Y, Fujiwara M, Hayakawa J, Ohmichi M, Koike K, Inoue M |
2000 |
| Base excision repair deficiency caused by polymerase beta haploinsufficiency: accelerated DNA damage and increased mutational response to carcinogens. |
Cabelof DC, Guo Z, Raffoul JJ, Sobol RW, Wilson SH, Richardson A, Heydari AR |
2003 |
| Cells deficient in DNA polymerase beta are hypersensitive to alkylating agent-induced apoptosis and chromosomal breakage. |
Ochs K, Sobol RW, Wilson SH, Kaina B |
1999 |
| Characterization of chromosome aberrations induced by incubation at a restrictive temperature in the mouse temperature-sensitive mutant tsFT20 strain containing heat-labile DNA polymerase alpha. |
Eki T, Enomoto T, Murakami Y, Hanaoka F, Yamada M |
1987 |
| Pol iota is a candidate for the mouse pulmonary adenoma resistance 2 locus, a major modifier of chemically induced lung neoplasia. |
Wang M, Devereux TR, Vikis HG, McCulloch SD, Holliday W, Anna C, Wang Y, Bebenek K, Kunkel TA, Guan K, You M |
2004 |
| Screening for deficits in DNA repair by the response of irradiated human lymphocytes to phytohemagglutinin. |
Agarwal SS, Brown DQ, Katz EJ, Loeb LA |
1977 |
| Restriction of carcinogen-induced error incorporation during in vitro DNA synthesis. |
Sirover MA, Loeb LA |
1976 |
| Studies on the induction of DNA polymerase during transformation of human lymphocytes. |
Agarwal SS, Loeb LA |
1972 |
| DNA polymerase and DNA replication during lymphocyte transformation. |
Loeb LA, Ewald JL, Agarwal SS |
1970 |
| Inhibitory effect of 1-beta-D-arabinofuranosylthymine 5'-triphosphate and 1-beta-D-arabinofuranosylcytosine 5'-triphosphate on DNA polymerases from murine cells and oncornavirus. |
Matsukage A, Ono K, Ohashi A, Takahashi T, Nakayama C, Saneyoshi M |
1978 |