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Polymerase: T4 L340P, Property: Nucleotide Substitution Rate

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Polymerase	Reference	Property	Result	Context
T4 L340P	Structure-function studies of the bacteriophage T4 DNA polymerase. Isolation of a novel suppressor mutant.	Nucleotide Substitution Rate	238 Mutation frequency (relative to WT)	Technique: T4 rII P7oc reversion assay (AT->TA(CG), Host: supD (CR63))
T4 L340P	Structure-function studies of the bacteriophage T4 DNA polymerase. Isolation of a novel suppressor mutant.	Nucleotide Substitution Rate	538 Mutation frequency (relative to WT)	Technique: T4 rII P7am reversion assay (GC->TA(CG), Host: supD (CR63))
T4 L340P	Structure-function studies of the bacteriophage T4 DNA polymerase. Isolation of a novel suppressor mutant.	Nucleotide Substitution Rate	1189 Mutation frequency (relative to WT)	Technique: ac forward mutational assay (Host: supE (MBM7007.2))
T4 L340P	Structure-function studies of the bacteriophage T4 DNA polymerase. Isolation of a novel suppressor mutant.	Nucleotide Substitution Rate	1744 Mutation frequency (relative to WT)	Technique: ac forward mutational assay (Host: supD (MBM7007.1))
T4 L340P	Structure-function studies of the bacteriophage T4 DNA polymerase. Isolation of a novel suppressor mutant.	Nucleotide Substitution Rate	1980 Mutation frequency (relative to WT)	Technique: T4 rII P7oc reversion assay (AT->GC, Host: supE (C600))
T4 L340P	Structure-function studies of the bacteriophage T4 DNA polymerase. Isolation of a novel suppressor mutant.	Nucleotide Substitution Rate	343 Mutation frequency (relative to WT)	Technique: T4 rII P7oc reversion assay (AT->TA(CG), Host: supE (C600))
T4 L340P	Structure-function studies of the bacteriophage T4 DNA polymerase. Isolation of a novel suppressor mutant.	Nucleotide Substitution Rate	742 Mutation frequency (relative to WT)	Technique: T4 rII P7am reversion assay (GC->TA(CG), Host: supE (C600))
T4 L340P	Structure-function studies of the bacteriophage T4 DNA polymerase. Isolation of a novel suppressor mutant.	Nucleotide Substitution Rate	941 Mutation frequency (relative to WT)	Technique: T4 rII 199oc reversion assay (AT->GC, Host: supD (CR63))
T4 L340P	Effect of temperature on transition and transversion mutagenesis: characterization of wild type and a mutator T4 DNA polymerase mutant.	Nucleotide Substitution Rate	2000 Mutation frequency (relative to WT)	Technique: T4 rII P7oc reversion assay (AT->GC pathway (P7oc -> P7am), 30°C)
T4 L340P	Effect of temperature on transition and transversion mutagenesis: characterization of wild type and a mutator T4 DNA polymerase mutant.	Nucleotide Substitution Rate	333 Mutation frequency (relative to WT)	Technique: T4 rII P7oc reversion assay (AT->TA(CG) pathway (P7oc -> rII+), 30°C)
T4 L340P	Effect of temperature on transition and transversion mutagenesis: characterization of wild type and a mutator T4 DNA polymerase mutant.	Nucleotide Substitution Rate	750 Mutation frequency (relative to WT)	Technique: T4 rII P7am reversion assay (GC->TA(CG) pathway (P7am -> rII+), 30°C)
T4 L340P	Studies on the biochemical basis of mutation VI. Selection and characterization of a new bacteriophage T4 mutator DNA polymerase.	Nucleotide Substitution Rate	55 Mutation frequency (relative to WT)	Technique: T4 rII 199oc reversion assay
T4 L340P	Amino acid changes coded by bacteriophage T4 DNA polymerase mutator mutants. Relating structure to function.	Nucleotide Substitution Rate	210 Mutation frequency (relative to WT)	Technique: ac forward mutational assay
T4 L340P	Isolation of bacteriophage T4 DNA polymerase mutator mutants.	Nucleotide Substitution Rate	380 Mutation frequency (relative to WT)	Technique: T4 rII P7oc reversion assay (AT->GC (P7oc->P7am))
T4 L340P	Isolation of bacteriophage T4 DNA polymerase mutator mutants.	Nucleotide Substitution Rate	320 Mutation frequency (relative to WT)	Technique: T4 rII P7oc reversion assay (AT->TA(CG) (P7oc->rII+))
T4 L340P	Isolation of bacteriophage T4 DNA polymerase mutator mutants.	Nucleotide Substitution Rate	1125 Mutation frequency (relative to WT)	Technique: T4 rII P7am reversion assay (GC->TA(CG) (P7am->rII+))