Human Pol eta
From
H. sapiens
(aliases:Polymerase eta)
(genes: POLH)
Welcome to the Polymerase Page
This page presents all the information in Polbase for Human Pol eta.
Mutants:At the top of the page you'll find a map of all positions of known mutants. Text links to mutants and digestion products are listed in the Mutants section.
Structures/Sequence:If available, a representative structure is displayed at the upper right. All known structures are listed in the Structures section.
External links:Polbase polymerases are linked to UniProt and Genbank where possible. The UniProt search link directs you to a pre-constructed UniProt search containing relevant terms.
References:All references that refer to this Polymerase are listed with their topics and paper's title in the References table.
Results:All the results for this polymerase can be examined by following the "Results" link at the bottom of the page.
Help icons:
The symbol in the upper-right corner of the page
links to this help text. The question mark icon is used everywhere to indicate that help is available.
Human Pol eta
is a family Y enzyme
from
H. sapiens.
Bypasses many template lesions
Selected Properties for Human Pol eta: |
3'-5' exo activity | 5'-3' exo activity | Frameshift Rate | Substitution Rate | General Error Rate |
|---|---|---|---|---|---|
| no consensus | no data | 2.4e-03 errors/bp (1) | 3.2e-02-3.6e-02 errors/bp (4) | 3.0e-02 errors/bp (1) |
- References (129)
- Structures (3)
- Sequences (1)
- Mutants (6)...
- Formulations (0)
- Polymerase Lots (0)
- External links
| Year | Authors | Title | Results by property |
|---|---|---|---|
| 2013 | Masayuki Yamada, Kenji Watanabe, Martin Mistrik, Eva Vesela, Iva Protivankova, Niels Mailand, Myunghee Lee, Hisao Masai, Jiri Lukas, Jiri Bartek | ATR-Chk1-APC/CCdh1-dependent stabiliz... | |
| 2013 | Yaofeng Zhao, Mark T Gregory, Christian Biertümpfel, Yue-Jin Hua, Fumio Hanaoka, Wei Wen Yang | Mechanism of somatic hypermutation at... | |
| 2013 | Michael Durando, Satoshi Tateishi, Cyrus Vaziri | A non-catalytic role of DNA polymeras... | |
| 2013 | Leena Maddukuri, Sarah C Shuck, Robert Lawton Eoff, Linlin Zhao, Carmelo J Rizzo, F Peter Guengerich, Lawrence J Marnett | Replication, Repair and Translesion P... | Template lesions,All properties |
| 2013 | DJ Taggart, Terry L Camerlengo, Jason K Harrison, Shanen M Sherrer, Ajay K Kshetry, John-Stephen Taylor, Kun Huang, Zucai Suo | A high-throughput and quantitative me... | |
| 2013 | Junpei Yamamoto, Tomoko Oyama, Tomohiro Kunishi, Chikahide Masutani, Fumio Hanaoka, Shigenori Iwai | A cyclobutane thymine-N4-methylcytosi... | |
| 2013 | Dechen Fu, Fred Duafalia Dudimah, Jun Zhang, Anna Pickering, Jayabal Paneerselvam, Manikandan Palrasu, Hong Wang, Peiwen Fei | Recruitment of DNA polymerase eta by ... | |
| 2012 | Shanen M Sherrer, DJ Taggart, Lindsey R Pack, Chanchal K Malik, Ashis K Basu, Zucai Suo | Quantitative analysis of the mutageni... | |
| 2012 | S Sharma, Nicholas A Shah, Ariell M Joiner, Katelyn H Roberts, CE Canman | DNA polymerase ζ is a major determina... | |
| 2012 | Ashley L Swanson, Jianshuang Wang, Yinsheng Wang | Accurate and Efficient Bypass of 8,5'... | |
| 2012 | Nils H Nicolay, Rebecca Carter, Stephanie B Hatch, Niklas Schultz, Remko Prevo, W Gillies McKenna, Thomas Helleday, Ricky A Sharma | Homologous recombination mediates S-p... | |
| 2012 | Yong-Sam Jung, Yingjuan Qian, Xinbin Chen | DNA polymerase eta is targeted by Mdm... | |
| 2012 | Alden C Klarer, L Jay Stallons, Tom J Burke, Robert L Skaggs, W Glenn McGregor | DNA polymerase eta participates in th... | |
| 2011 | Thomas Göhler, Simone Sabbioneda, Catherine M Green, Alan R Lehmann | ATR-mediated phosphorylation of DNA p... | |
| 2011 | Kai-Ming Chou | DNA polymerase eta and chemotherapeut... | |
| 2011 | Christian Biertümpfel, Yaofeng Zhao, Yuji Kondo, Santiago Ramón-Maiques, Mark T Gregory, Jae Young Lee, Chikahide Masutani, Alan R Lehmann, Fumio Hanaoka, Wei Wen Yang | Structure and mechanism of human DNA ... | |
| 2011 | Ajay Ummat, Timothy D Silverstein, Rinku Jain, Angeliki Buku, Robert E Johnson, Louise Prakash, Satya Prakash, Aneel K Aggarwal | Human DNA Polymerase η Is Pre-Aligned... | |
| 2010 | Séverine Cruet-Hennequart, Kathleen Gallagher, Anna M Sokòl, Sangamitra Villalan, Aine M Prendergast, Michael P Carty | DNA polymerase eta, a key protein in ... | |
| 2010 | Yong-Sam Jung, Gang Liu, Xinbin Chen | Pirh2 E3 ubiquitin ligase targets DNA... | |
| 2010 | Mark D Sutton | Coordinating DNA polymerase traffic d... | |
| 2010 | Christian Biertümpfel, Yaofeng Zhao, Yuji Kondo, Santiago Ramón-Maiques, Mark T Gregory, Jae Young Lee, Chikahide Masutani, Alan R Lehmann, Fumio Hanaoka, Wei Wen Yang | Structure and mechanism of human DNA ... | |
| 2010 | Takayuki Sekimoto, Tsukasa Oda, Franklin Mayca Pozo, Yoshiki Murakumo, Chikahide Masutani, Fumio Hanaoka, Takayuki Yamashita | The molecular chaperone Hsp90 regulat... | |
| 2010 | Tovah A Day, Komariah Palle, Laura R Barkley, Naoko Kakusho, Ying Zou, Satoshi Tateishi, Alain Verreault, Hisao Masai, Cyrus Vaziri | Phosphorylated Rad 18 directs DNA Pol... | |
| 2010 | Sayo Kashiwagi, Isao Kuraoka, Yoshie Fujiwara, Kenichi Hitomi, Quen J Cheng, Jill O Fuss, David S Shin, Chikahide Masutani, John A Tainer, Fumio Hanaoka, Shigenori Iwai | Characterization of a Y-Family DNA Po... | |
| 2010 | Katarzyna Bebenek, Miguel Garcia-Diaz, Rui-Zhe Zhou, Lawrence F Povirk, Thomas A Kunkel | Loop 1 modulates the fidelity of DNA ... | |
| 2010 | Jessica A Brown, Likui Zhang, Shanen M Sherrer, John-Stephen Taylor, Peter M J Burgers, Zucai Suo | Pre-Steady-State Kinetic Analysis of ... | 3-5' exo,5-3' exo,All properties |
| 2009 | Dorjbal Dorjsuren, David M Wilson, William A Beard, John P McDonald, Christopher P Austin, Roger Woodgate, Samuel H Wilson, Anton Simeonov | A real-time fluorescence method for e... | |
| 2009 | Simone Sabbioneda, Catherine M Green, Marzena Bienko, Patricia L Kannouche, Ivan Dikic, Alan R Lehmann | Ubiquitin-binding motif of human DNA ... | |
| 2009 | Laurie Rey, Julia M Sidorova, Nadine Puget, François Boudsocq, Denis S F Biard, Raymond J Monnat, Christophe Cazaux, Jean-Sébastien Hoffmann | Human DNA polymerase eta is required ... | |
| 2009 | Kazuya Satou, Mika Hori, Kazuaki Kawai, Hiroshi Kasai, Hideyoshi Harashima, Hiroyuki Kamiya | Involvement of specialized DNA polyme... | |
| 2009 | Xiao Meng, Yanjiao Zhou, Sufang Zhang, Ernest Y C Lee, David N Frick, Marietta Y W T Lee | DNA damage alters DNA polymerase delt... | |
| 2009 | Jennifer B Stafford, Robert Lawton Eoff, Albena Kozekova, Carmelo J Rizzo, F Peter Guengerich, Lawrence J Marnett | Translesion DNA synthesis by human DN... | |
| 2009 | Scott D McCulloch, Robert J Kokoska, Parie Garg, Peter M J Burgers, Thomas A Kunkel | The efficiency and fidelity of 8-oxo-... | |
| 2009 | Rémy Bétous, Laurie Rey, Guliang Wang, Marie-Jeanne Pillaire, Nadine Puget, Janick Selves, Denis S F Biard, Kazuo Shin-ya, Karen M Vasquez, Christophe Cazaux, Jean-Sébastien Hoffmann | Role of TLS DNA polymerases eta and k... | |
| 2009 | Asami Hishiki, Hiroshi Hashimoto, Tomo Hanafusa, Keijiro Kamei, Eiji Ohashi, Toshiyuki Shimizu, Haruo Ohmori, Mamoru Sato | Structural basis for novel interactio... | |
| 2009 | Rie Kanao, Fumio Hanaoka, Chikahide Masutani | A novel interaction between human DNA... | |
| 2008 | Yih-Wen Chen, James E Cleaver, Zafer Hatahet, Richard E Honkanen, Jang-Yang Chang, Yun Yen, Kai-Ming Chou | Human DNA polymerase eta activity and... | |
| 2008 | Linda J Reha-Krantz | Recent patents of gene sequences rela... | |
| 2008 | Narottam Acharya, Jung-Hoon Yoon, Himabindu Gali, Ildiko Unk, Lajos Haracska, Robert E Johnson, Jerard Hurwitz, Louise Prakash, Satya Prakash | Roles of PCNA-binding and ubiquitin-b... | |
| 2008 | Katsuhiko Hidaka, Masami Yamada, Hiroyuki Kamiya, Chikahide Masutani, Hideyoshi Harashima, Fumio Hanaoka, Takehiko Nohmi | Specificity of mutations induced by i... | |
| 2008 | Junpei Yamamoto, David Loakes, Chikahide Masutani, Shizu Simmyo, Kumiko Urabe, Fumio Hanaoka, Philipp Holliger, Shigenori Iwai | Translesion synthesis across the (6-4... | |
| 2008 | Patrick P Lestienne, François Boudsocq, Jacques E Bonnet | Initiation of DNA replication by a th... | |
| 2008 | Laureen C Colis, Paromita Raychaudhury, Ashis K Basu | Mutational specificity of gamma-radia... | |
| 2008 | Nana Nikolaishvili-Feinberg, G Scott Jenkins, Kathleen R Nevis, Dean P Staus, Cameron O Scarlett, Keziban Unsal-Kaçmaz, William K Kaufmann, Marila Cordeiro-Stone | Ubiquitylation of proliferating cell ... | Template lesions,All properties |
| 2008 | Scott D McCulloch, Thomas A Kunkel | The fidelity of DNA synthesis by euka... | Frameshift Error Rate,Nucleotide Substitution Rate,All properties |
| 2007 | Narottam Acharya, Amrita Brahma, Lajos Haracska, Louise Prakash, Satya Prakash | Mutations in the ubiquitin binding UB... | |
| 2007 | Flavia Barone, Scott D McCulloch, Peter Macpherson, Giovanni Maga, Masami Yamada, Takehiko Nohmi, Anna Minoprio, Filomena Mazzei, Thomas A Kunkel, Peter Karran, Margherita Bignami | Replication of 2-hydroxyadenine-conta... | |
| 2007 | Hirotomo Nakata, Masayuki Amano, Yasuhiro Koh, Eiichi N Kodama, Guangwei Yang, Christopher M Bailey, Satoru Kohgo, Hiroyuki Hayakawa, Masao Matsuoka, Karen S Anderson, Yung-Chi Cheng, Hiroyuki Mitsuya | Activity against human immunodeficien... | |
| 2007 | Masatomi Shimizu, Petr Grúz, Hiroyuki Kamiya, Chikahide Masutani, Yan Xu, Yukio Usui, Hiroshi Sugiyama, Hideyoshi Harashima, Fumio Hanaoka, Takehiko Nohmi | Efficient and erroneous incorporation... | |
| 2007 | Jessica A Brown, Wade W Duym, Jason D Fowler, Zucai Suo | Single-turnover kinetic analysis of t... | |
| 2007 | Martha G Bomar, Ming-Tao Pai, Shiou-Ru Tzeng, Shawn Shun-Cheng Li, Pei Zhou | Structure of the ubiquitin-binding zi... | |
| 2007 | Wei Wen Yang, Roger Woodgate | What a difference a decade makes: ins... | |
| 2006 | Scott D McCulloch, Thomas A Kunkel | Measuring the fidelity of translesion... | |
| 2006 | Jeong-Yun Choi, Goutam Chowdhury, Hong Zang, Karen C Angel, Choua C Vu, Lisa A Peterson, F Peter Guengerich | Translesion synthesis across O6-alkyl... | |
| 2006 | Séverine Cruet-Hennequart, Seamus Coyne, Macdara T Glynn, Gregory G Oakley, Michael P Carty | UV-induced RPA phosphorylation is inc... | |
| 2006 | Bo Zhao, Jianhong Wang, Nicholas E Geacintov, Zhengqiang Wang | Poleta, Polzeta and Rev1 together are... | |
| 2006 | Chiu Hong Lee, Sushil Chandani, Edward L Loechler | Homology modeling of four Y-family, l... | |
| 2006 | Jeong-Yun Choi, James S Stover, Karen C Angel, Goutam Chowdhury, Carmelo J Rizzo, F Peter Guengerich | Biochemical basis of genotoxicity of ... | |
| 2006 | Mayumi S Yuasa, Chikahide Masutani, Akihiko Hirano, Martin A Cohn, Masaru Yamaizumi, Yoshihiro Nakatani, Fumio Hanaoka | A human DNA polymerase eta complex co... | |
| 2006 | Keronninn Moreno Lima-Bessa, Vanessa Chiganças, Anne Stary, Patricia L Kannouche, Alain Sarasin, Melissa Gava Armelini, Jacqueline de Fátima Jacysyn, Gustavo P Amarante-Mendes, Marila Cordeiro-Stone, James E Cleaver, Carlos Frederico Martins Menck | Adenovirus mediated transduction of t... | |
| 2005 | Nicole M King, Nana Nikolaishvili-Feinberg, Miriam F Bryant, Douglas D Luche, Timothy P Heffernan, Dennis A Simpson, Fumio Hanaoka, William K Kaufmann, Marila Cordeiro-Stone | Overproduction of DNA polymerase eta ... | |
| 2005 | Michael J McIlwraith, Michael J Mcllwraith, Alexandra Vaisman, Yilun Liu, Ellen Fanning, Roger Woodgate, Stephen C West | Human DNA polymerase eta promotes DNA... | |
| 2005 | Dominic Chiapperino, Mangmang Cai, Jane M Sayer, Haruhiko Yagi, Heiko Kroth, Chikahide Masutani, Fumio Hanaoka, Donald M Jerina, Albert M Cheh | Error-prone translesion synthesis by ... | |
| 2005 | Wei Wen Yang | Portraits of a Y-family DNA polymerase. | |
| 2005 | Jeong-Yun Choi, F Peter Guengerich | Adduct size limits efficient and erro... | |
| 2005 | Takehiko Nohmi, Su-Ryang Kim, Masami Yamada | Modulation of oxidative mutagenesis a... | |
| 2005 | Emmanuele Crespan, Samantha Zanoli, Anastasiya Khandazhinskaya, Igor V Shevelev, Maxim Jasko, Ludmila Alexandrova, Marina Kukhanova, Giuseppina Blanca, Giuseppe Villani, Ulrich Hübscher, Silvio Spadari, Giovanni Maga | Incorporation of non-nucleoside triph... | |
| 2005 | Satya Prakash, Robert E Johnson, Louise Prakash | Eukaryotic translesion synthesis DNA ... | |
| 2005 | Robert E Johnson, Louise Prakash, Satya Prakash | Distinct mechanisms of cis-syn thymin... | |
| 2005 | William T Wolfle, Robert E Johnson, Irina G Minko, R Stephen Lloyd, Satya Prakash, Louise Prakash | Human DNA polymerase iota promotes re... | |
| 2004 | Scott D McCulloch, Robert J Kokoska, Chikahide Masutani, Shigenori Iwai, Fumio Hanaoka, Thomas A Kunkel | Preferential cis-syn thymine dimer by... | |
| 2004 | Rika Kusumoto, Chikahide Masutani, Shizu Shimmyo, Shigenori Iwai, Fumio Hanaoka | DNA binding properties of human DNA p... | |
| 2004 | Patricia L Kannouche, Jonathan Wing, Alan R Lehmann | Interaction of human DNA polymerase e... | |
| 2004 | Katuhito Kino, Nobutoshi Ito, Kaoru Sugasawa, Hiroshi Sugiyama, Fumio Hanaoka | Translesion synthesis by human DNA po... | |
| 2004 | Giuseppina Blanca, Giuseppe Villani, Igor V Shevelev, Kristijan Ramadan, Silvio Spadari, Ulrich Hübscher, Giovanni Maga | Human DNA polymerases lambda and beta... | |
| 2004 | Kenji Watanabe, Satoshi Tateishi, Michio Kawasuji, Toshiki Tsurimoto, Hirokazu Inoue, Masaru Yamaizumi | Rad18 guides poleta to replication st... | |
| 2004 | Scott D McCulloch, Robert J Kokoska, Thomas A Kunkel | Efficiency, fidelity and enzymatic sw... | |
| 2004 | Naomi Suzuki, Manabu Yasui, Y R Santosh Laxmi, Haruo Ohmori, Fumio Hanaoka, Shinya Shibutani | Translesion synthesis past equine est... | |
| 2004 | Naomi Suzuki, Shinji Itoh, Kinning Poon, Chikahide Masutani, Fumio Hanaoka, Haruo Ohmori, Itsuo Yoshizawa, Shinya Shibutani | Translesion synthesis past estrogen-d... | |
| 2004 | Kohei Takasawa, Chikahide Masutani, Fumio Hanaoka, Shigenori Iwai | Chemical synthesis and translesion re... | |
| 2003 | Robert J Kokoska, Scott D McCulloch, Thomas A Kunkel | The efficiency and specificity of apu... | |
| 2003 | Robert E Johnson, José Trincao, Aneel K Aggarwal, Satya Prakash, Louise Prakash | Deoxynucleotide triphosphate binding ... | |
| 2003 | Thomas A Kunkel, Youri I Pavlov, Katarzyna Bebenek | Functions of human DNA polymerases et... | Full length or truncated,3-5' exo,Nucleotide Substitution Rate,Template lesions,All properties |
| 2003 | Eitan Glick, Janice S Chau, Kellie L Vigna, Scott D McCulloch, Elinor T Adman, Thomas A Kunkel, Lawrence A Loeb | Amino acid substitutions at conserved... | KM,Vmax,Associated condition,Template lesions,All properties |
| 2003 | M Todd Washington, Robert E Johnson, Louise Prakash, Satya Prakash | The mechanism of nucleotide incorpora... | |
| 2003 | M Todd Washington, William T Wolfle, Thomas E Spratt, Louise Prakash, Satya Prakash | Yeast DNA polymerase eta makes functi... | |
| 2003 | M Todd Washington, Sandra A Helquist, Eric T Kool, Louise Prakash, Satya Prakash | Requirement of Watson-Crick hydrogen ... | |
| 2003 | Irina G Minko, M Todd Washington, Manorama Kanuri, Louise Prakash, Satya Prakash, R Stephen Lloyd | Translesion synthesis past acrolein-d... | |
| 2002 | Dominic Chiapperino, Heiko Kroth, Irene H Kramarczuk, Jane M Sayer, Chikahide Masutani, Fumio Hanaoka, Donald M Jerina, Albert M Cheh | Preferential misincorporation of puri... | |
| 2002 | Ulrich Hubscher, Giovanni Maga, Silvio Spadari | Eukaryotic DNA polymerases. | |
| 2002 | François Boudsocq, Hong Ling, Wei Wen Yang, Roger Woodgate | Structure-based interpretation of mis... | |
| 2002 | Rika Kusumoto, Chikahide Masutani, Shigenori Iwai, Fumio Hanaoka | Translesion synthesis by human DNA po... | |
| 2002 | Yongqing Zhang, Xiaoming Wu, Dongyu Guo, Olga Rechkoblit, Nicholas E Geacintov, Zhengqiang Wang | Two-step error-prone bypass of the (+... | |
| 2002 | Lajos Haracska, Louise Prakash, Satya Prakash | Role of human DNA polymerase kappa as... | |
| 2001 | M Todd Washington, Robert E Johnson, Satya Prakash, Louise Prakash | Mismatch extension ability of yeast a... | |
| 2001 | Patricia J Gearhart, Richard D Wood | Emerging links between hypermutation ... | Associated condition,Template lesions,Overall Error Rate,All properties |
| 2001 | Isao Kuraoka, P Robins, Chikahide Masutani, Fumio Hanaoka, Didier Gasparutto, Jean Cadet, Richard D Wood, T Lindahl | Oxygen free radical damage to DNA. Tr... | |
| 2001 | M Todd Washington, Robert E Johnson, Louise Prakash, Satya Prakash | Accuracy of lesion bypass by yeast an... | |
| 2001 | Phillip A Furman, J Jeffrey, L L Kiefer, Joy Y Feng, Karen S Anderson, K Borroto-Esoda, E Hill, William C Copeland, Chung K Chu, J P Sommadossi, I Liberman, Raymond F Schinazi, George R Painter | Mechanism of action of 1-beta-D-2,6-d... | |
| 2001 | Eitan Glick, Kellie L Vigna, Lawrence A Loeb | Mutations in human DNA polymerase eta... | |
| 2001 | Toshiro Matsuda, Katarzyna Bebenek, Chikahide Masutani, Igor B Rogozin, Fumio Hanaoka, Thomas A Kunkel | Error rate and specificity of human a... | Cloned or native,Tagged,Tag Name,Full length or truncated,Gap fill,3-5' exo,Nucleotide Substitution Rate,All properties |
| 2001 | Katarzyna Bebenek, Toshiro Matsuda, Chikahide Masutani, Fumio Hanaoka, Thomas A Kunkel | Proofreading of DNA polymerase eta-de... | |
| 2001 | A J Podlutsky, Irina I Dianova, Vladimir N Podust, Vilhelm A Bohr, Grigory L Dianov | Human DNA polymerase beta initiates D... | |
| 2001 | Lajos Haracska, Robert E Johnson, Ildiko Unk, B Phillips, Jerard Hurwitz, Louise Prakash, Satya Prakash | Physical and functional interactions ... | |
| 2001 | M Todd Washington, Louise Prakash, Satya Prakash | Yeast DNA polymerase eta utilizes an ... | Processivity,Kd,kcat,Vmax,All properties |
| 2000 | K Nagasawa, K Kitamura, Akira Yasui, Y Nimura, Kyoji Ikeda, Midori Hirai, Akio Matsukage, Makoto Nakanishi | Identification and characterization o... | |
| 2000 | Toshiro Matsuda, Katarzyna Bebenek, Chikahide Masutani, Fumio Hanaoka, Thomas A Kunkel | Low fidelity DNA synthesis by human D... | 3-5' exo,All properties |
| 2000 | Robert E Johnson, M Todd Washington, Satya Prakash, Louise Prakash | Fidelity of human DNA polymerase eta. | |
| 2000 | Agnès Tissier, John P McDonald, Ekaterina G Frank, Roger Woodgate | poliota, a remarkably error-prone hum... | |
| 2000 | Eiji Ohashi, Katarzyna Bebenek, Toshiro Matsuda, William J Feaver, Valerie L Gerlach, Errol C Friedberg, Haruo Ohmori, Thomas A Kunkel | Fidelity and processivity of DNA synt... | Nucleotide Substitution Rate,All properties |
| 2000 | Yongqing Zhang, Fenghua Yuan, Xiaoming Wu, Olga Rechkoblit, John-Stephen Taylor, Nicholas E Geacintov, Zhengqiang Wang | Error-prone lesion bypass by human DN... | |
| 2000 | Lajos Haracska, Satya Prakash, Louise Prakash | Replication past O(6)-methylguanine b... | |
| 2000 | Chikahide Masutani, Rika Kusumoto, Shigenori Iwai, Fumio Hanaoka | Mechanisms of accurate translesion sy... | |
| 2000 | Satya Prakash, Robert E Johnson, M Todd Washington, Lajos Haracska, Christine M Kondratick, Louise Prakash | Role of yeast and human DNA polymeras... | |
| 2000 | Alexandra Vaisman, Chikahide Masutani, Fumio Hanaoka, Stephen G Chaney | Efficient translesion replication pas... | |
| 1999 | E Efrati, G Tocco, R Eritja, Samuel H Wilson, Myron F Goodman | "Action-at-a-distance" mutagenesis. 8... | |
| 1999 | T A Winters, P S Russell, M Kohli, M E Dar, R D Neumann, T J Jorgensen | Determination of human DNA polymerase... | |
| 1999 | J M de Muys, H Gourdeau, N Nguyen-Ba, D L Taylor, P S Ahmed, T Mansour, C Locas, N Richard, Mark A. Wainberg, R F Rando | Anti-human immunodeficiency virus typ... | |
| 1999 | N B Reuven, Gali Arad, Ayelet Maor-Shoshani, Zvi Livneh | The mutagenesis protein UmuC is a DNA... | |
| 1999 | Chikahide Masutani, Rika Kusumoto, Ayumi Yamada, N Dohmae, Masayuki Yokoi, M Yuasa, M Araki, Shigenori Iwai, K Takio, Fumio Hanaoka | The XPV (xeroderma pigmentosum varian... | |
| 1999 | Farida S Sharief, P J Vojta, P A Ropp, William C Copeland | Cloning and chromosomal mapping of th... | |
| 1997 | E Efrati, G Tocco, R Eritja, Samuel H Wilson, Myron F Goodman | Abasic translesion synthesis by DNA p... | |
| 1995 | Federico Focher, Giovanni Maga, A Bendiscioli, M Capobianco, F Colonna, A Garbesi, Silvio Spadari | Stereospecificity of human DNA polyme... | |
| 1995 | R R Vyas, A K Basu | DNA polymerase action on an oligonucl... | |
| 1993 | M S Chen, R T Suttmann, E Papp, P D Cannon, M J McRoberts, C Bach, William C Copeland, Teresa S-F Wang | Selective action of 4'-azidothymidine... | |
| 1992 | William C Copeland, M S Chen, Teresa S-F Wang | Human DNA polymerases alpha and beta ... | |
| 1991 | K B Frank, G J Noll, E V Connell, I S Sim | Kinetic interaction of human immunode... | |
| 1989 | J E Reardon | Herpes simplex virus type 1 and human... | |
| 1988 | H Nakane, Jan Balzarini, Erik De Clercq, K Ono | Differential inhibition of various de... |
Protein sequence:
| Name | 3'-5' exo activity | 5'-3' exo activity | Frameshift Rate | Substitution Rate | General Error Rate |
|---|---|---|---|---|---|
| Pol eta Y52E | No (1) | No (1) | |||
| Pol eta Y52D | |||||
| Pol eta Y52H | |||||
| Pol eta Y52F | No (1) | No (1) | |||
| Pol eta Y52A | No (1) | No (1) | |||
| Human Pol eta D652A |
Protein information: Uniprot Q9Y253 search for Human Pol eta at UniProt
Sequence information: NCBI nucleotides European nucleotide archive