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Polymerase: T4 D219A, Property: Nucleotide Substitution Rate

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Polymerase Reference Property Result Context
T4 D219A Genetic and biochemical studies of bacteriophage T4 DNA polymerase 3'-->5'-exonuclease activity. Nucleotide Substitution Rate 500 Mutation frequency (relative to WT) Technique: T4 rII 199oc reversion assay
T4 D219A Construction and characterization of a bacteriophage T4 DNA polymerase deficient in 3'-->5' exonuclease activity. Nucleotide Substitution Rate 760 Mutation frequency (relative to WT) Technique: ac forward mutational assay
T4 D219A Effect of accessory proteins on T4 DNA polymerase replication fidelity. Nucleotide Substitution Rate 4E-05 errors/bp Technique: M13mp2 forward mutation assay
T4 D219A Effect of accessory proteins on T4 DNA polymerase replication fidelity. Nucleotide Substitution Rate 0.0001 errors/bp Technique: M13mp2 opal codon reversion assay

Version:20241007

Using Polbase tables:

Sorting:

Tables may be sorted by clicking on any of the column titles. A second click reverses the sort order. <Ctrl> + click on the column titles to sort by more than one column (e.g. family then name).

Filtering:

It is also possible to filter the table by typing into the search box above the table. This will instantly hide lines from the table that do not contain your search text.