Human Pol epsilon
From
H. sapiens
(aliases:Hsa pol epsilon)
(genes: POLE)
Welcome to the Polymerase Page
This page presents all the information in Polbase for Human Pol epsilon.
Mutants:At the top of the page you'll find a map of all positions of known mutants. Text links to mutants and digestion products are listed in the Mutants section.
Structures/Sequence:If available, a representative structure is displayed at the upper right. All known structures are listed in the Structures section.
External links:Polbase polymerases are linked to UniProt and Genbank where possible. The UniProt search link directs you to a pre-constructed UniProt search containing relevant terms.
References:All references that refer to this Polymerase are listed with their topics and paper's title in the References table.
Results:All the results for this polymerase can be examined by following the "Results" link at the bottom of the page.
Help icons:
The symbol in the upper-right corner of the page
links to this help text. The question mark icon is used everywhere to indicate that help is available.
Human Pol epsilon
is a family B enzyme
from
H. sapiens.
- References (51)
- Structures (1)
- Sequences (1)
- Mutants (0)...
- Formulations (0)
- Polymerase Lots (0)
- External links
| Year | Authors | Title | Results by property |
|---|---|---|---|
| 2013 | Valentina Aria, Mariarita De Felice, Roberta Di Perna, Shuji Uno, Hisao Masai, Juhani E Syvaoja, Barbara van Loon, Ulrich Hubscher, Francesca M Pisani | The Human Tim/Tipin Complex Directly ... | |
| 2013 | Walter J Zahurancik, Seth J Klein, Zucai Suo | Kinetic Mechanism of DNA Polymerizati... | |
| 2012 | Markku Vaara, Harri Itkonen, Tomi Hillukkala, Zhe Liu, Heinz Peter Nasheuer, Daniel Schaarschmidt, Helmut Pospiech, Juhani E Syväoja | Segregation of replicative DNA polyme... | |
| 2011 | Alan B Clark, Scott A Lujan, Grace E Kissling, Thomas A Kunkel | Mismatch repair-independent tandem re... | |
| 2011 | Dagmara A Korona, Kimberly G Lecompte, Zachary F Pursell | The high fidelity and unique error si... | |
| 2010 | Christopher Van, Shan Yan, W Matthew Michael, Shou Waga, Karlene A Cimprich | Continued primer synthesis at stalled... | |
| 2010 | Stephanie A Nick McElhinny, Brian E Watts, Dinesh Kumar, Danielle L Watt, Else-Britt Lundström, Peter M J Burgers, Erik Johansson, Andrei Chabes, Thomas A Kunkel | Abundant ribonucleotide incorporation... | |
| 2010 | Mark D Sutton | Coordinating DNA polymerase traffic d... | |
| 2009 | Yuki Matsui, Takahiko Hada, Naoki Maeda, Yoshihiro Sato, Yasuhiro Yamaguchi, Toshifumi Takeuchi, Masaharu Takemura, Fumio Sugawara, Kengo Sakaguchi, Hiromi Yoshida, Yoshiyuki Mizushina | Structure and activity relationship o... | |
| 2009 | Tahir H Tahirov, Kira S Makarova, Igor B Rogozin, Youri I Pavlov, Eugene V Koonin | Evolution of DNA polymerases: an inac... | 3-5' exo,5-3' exo,All properties |
| 2008 | Tarmo Nuutinen, Helena Tossavainen, Kai Fredriksson, Päivi Pirilä, Perttu Permi, Helmut Pospiech, Juhani E Syvaoja | The solution structure of the amino-t... | |
| 2006 | Anna K Rytkönen, Tomi Hillukkala, Markku Vaara, Miiko Sokka, Maarit Jokela, Raija Sormunen, Heinz Peter Nasheuer, Tamar Nethanel, Gabriel Kaufmann, Helmut Pospiech, Juhani E Syväoja | DNA polymerase epsilon associates wit... | Other accessory protein(s),All properties |
| 2004 | Youri I Pavlov, Satoko Maki, Hisaji Maki, Thomas A Kunkel | Evidence for interplay among yeast re... | 3-5' exo,5-3' exo,All properties |
| 2004 | Masahiko Oshige, Ryo Takeuchi, Tatsuji Ruike, Ryuji Ruike, Kazufumi Kuroda, Kengo Sakaguchi | Subunit protein-affinity isolation of... | 3-5' exo,All properties |
| 2003 | Yoshiyuki Mizushina, Xianai Xu, Hitomi Asahara, Ryo Takeuchi, Masahiko Oshige, Noriko Shimazaki, Masaharu Takemura, Tsuyoshi Yamaguchi, Kazufumi Kuroda, Stuart Linn, Hiromi Yoshida, Osamu Koiwai, Mineo Saneyoshi, Fumio Sugawara, Kengo Sakaguchi | A sulphoquinovosyl diacylglycerol is ... | |
| 2003 | Hitomi Asahara, Yingqian Li, Jill Fuss, Dale S Haines, Nikolina Vlatkovic, Mark T Boyd, Stuart Linn | Stimulation of human DNA polymerase e... | |
| 2002 | Ulrich Hubscher, Giovanni Maga, Silvio Spadari | Eukaryotic DNA polymerases. | |
| 2002 | Jill Fuss, Stuart Linn | Human DNA polymerase epsilon colocali... | |
| 2002 | Yoshiyuki Mizushina, Shinji Kamisuki, Nobuyuki Kasai, Tomomi Ishidoh, Noriko Shimazaki, Masaharu Takemura, Hitomi Asahara, Stuart Linn, Shonen Yoshida, Osamu Koiwai, Fumio Sugawara, Hiromi Yoshida, Kengo Sakaguchi | Petasiphenol: a DNA polymerase lambda... | |
| 2000 | S W Wang, T Toda, R MacCallum, A L Harris, C Norbury | Cid1, a fission yeast protein require... | |
| 2000 | W Liu, Stuart Linn | Proteolysis of the human DNA polymera... | |
| 1999 | T A Winters, P S Russell, M Kohli, M E Dar, R D Neumann, T J Jorgensen | Determination of human DNA polymerase... | |
| 1999 | Helmut Pospiech, I Kursula, Waleed Abdel-Aziz, Linda Malkas, L Uitto, M Kastelli, M Vihinen-Ranta, S Eskelinen, Juhani E Syväoja | A neutralizing antibody against human... | |
| 1998 | Maarit Jokela, M Mäkiniemi, S Lehtonen, C Szpirer, U Hellman, Juhani E Syväoja | The small subunits of human and mouse... | |
| 1998 | A Tomikawa, M Seno, K Sato-Kiyotaki, C Ohtsuki, T Hirai, Tsuyoshi Yamaguchi, T Kawaguchi, Shonen Yoshida, Mineo Saneyoshi | Synthetic nucleosides and nucleotides... | |
| 1997 | Yingqian Li, Hitomi Asahara, V S Patel, S Zhou, Stuart Linn | Purification, cDNA cloning, and gene ... | |
| 1996 | S Ceccotti, G Aquilina, Peter Macpherson, Masami Yamada, Peter Karran, Margherita Bignami | Processing of O6-methylguanine by mis... | |
| 1996 | Dmitry Ju Mozzherin, Paul A Fisher | Human DNA polymerase epsilon: enzymol... | |
| 1996 | F B Perler, Sandeep Kumar, H Kong | Thermostable DNA polymerases. | Full length or truncated,3-5' exo,5-3' exo,All properties |
| 1996 | Kenji Kamiya, P Huang, W Plunkett | Inhibition of the 3' --> 5' exonuclea... | |
| 1996 | Polina V Shcherbakova, V N Noskov, M R Pshenichnov, Youri I Pavlov | Base analog 6-N-hydroxylaminopurine m... | |
| 1995 | G Chui, Stuart Linn | Further characterization of HeLa DNA ... | Cloned or native,Tagged,Full length or truncated,Extension from RNA primer,Percent/Fold Effect,All properties |
| 1995 | T A Navas, Z Zhou, S J Elledge | DNA polymerase epsilon links the DNA ... | |
| 1995 | Federico Focher, Giovanni Maga, A Bendiscioli, M Capobianco, F Colonna, A Garbesi, Silvio Spadari | Stereospecificity of human DNA polyme... | |
| 1994 | Xincang Li, Peter M J Burgers | Molecular cloning and expression of t... | |
| 1994 | L M Podust, Vladimir N Podust, C Floth, Ulrich Hübscher | Assembly of DNA polymerase delta and ... | |
| 1993 | Tapio Kesti, H Frantti, Juhani E Syväoja | Molecular cloning of the cDNA for the... | |
| 1993 | Vladimir N Podust, Ulrich Hübscher | Lagging strand DNA synthesis by calf ... | |
| 1992 | L Uitto, J Halleen, P Remes, Tapio Kesti, Juhani E Syväoja | The 3'-->5' exonuclease associated wi... | |
| 1992 | Dmitry A Gordenin, A L Malkova, A Peterzen, V N Kulikov, Youri I Pavlov, E Perkins, Michael A Resnick | Transposon Tn5 excision in yeast: inf... | |
| 1992 | DNA Replication | ||
| 1992 | Hiroyuki Araki, P A Ropp, A L Johnson, L H Johnston, A Morrison, Akio Sugino | DNA polymerase II, the probable homol... | |
| 1992 | H Hao, Yanan Jiang, S J Zhang, Peiming Zhang, R X Zeng, Marietta Y W T Lee | Structural and functional relationshi... | |
| 1991 | T Weiser, M Gassmann, P Thömmes, Elena Ferrari, P Hafkemeyer, Ulrich Hübscher | Biochemical and functional comparison... | Full length or truncated,Specific Activity,Processivity,3-5' exo,5-3' exo,3-5' Exo Specific Activity,RNase H,All properties |
| 1991 | Sang Hee Lee, Z Q Pan, A D Kwong, Peter M J Burgers, Jerard Hurwitz | Synthesis of DNA by DNA polymerase ep... | |
| 1991 | Alessandra Montecucco, M Fontana, Federico Focher, M Lestingi, Silvio Spadari, G Ciarrocchi | Specific inhibition of human DNA liga... | |
| 1990 | Peter M J Burgers, Robert A Bambara, Judith L Campbell, L M Chang, Kathleen M Downey, Ulrich Hübscher, Marietta Y W T Lee, Stuart Linn, Antero G So, Silvio Spadari | Revised nomenclature for eukaryotic D... | |
| 1989 | J Syvaoja, Stuart Linn | Characterization of a large form of D... | Cloned or native,Tagged,Full length or truncated,Specific Activity,Processivity,3-5' exo,KM,Molecular Weight,All properties |
| 1987 | Marietta Y W T Lee, N L Toomey | Human placental DNA polymerase delta:... | |
| 1981 | M Geuskens, N Hardt, G Pedrali-Noy, Silvio Spadari | An autoradiographic demonstration of ... | |
| 1980 | G Pedrali-Noy, Silvio Spadari, A Miller-Faurès, A O Miller, J Kruppa, G Koch | Synchronization of HeLa cell cultures... |
Protein sequence:
Protein information: Uniprot Q07864 search for Human Pol epsilon at UniProt
Sequence information: NCBI nucleotides European nucleotide archive