Vaccinia Virus Pol

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Welcome to the Polymerase Page

This page presents all the information in Polbase for Vaccinia Virus Pol.

Mutants:

At the top of the page you'll find a map of all positions of known mutants. Text links to mutants and digestion products are listed in the Mutants section.

Structures/Sequence:

If available, a representative structure is displayed at the upper right. All known structures are listed in the Structures section.

External links:

Polbase polymerases are linked to UniProt and Genbank where possible. The UniProt search link directs you to a pre-constructed UniProt search containing relevant terms.

References:

All references that refer to this Polymerase are listed with their topics and paper's title in the References table.

Results:

All the results for this polymerase can be examined by following the "Results" link at the bottom of the page.

Help icons:

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Vaccinia Virus Pol is a family B enzyme from Vaccinia Virus.

Selected Properties for Vaccinia Virus Pol:

3'-5' exo activity 5'-3' exo activity Frameshift Rate Substitution Rate General Error Rate
Yes (2) no consensus no data no data no data
Year Authors Title Results by property
2014 Céline Contesto-Richefeu, Nicolas Tarbouriech, Xavier Brazzolotto, Stéphane Betzi, Xavier Morelli, Wim P Burmeister, Frédéric Iseni Crystal structure of the vaccinia vir...
2012 Chad R Irwin, Andrew Farmer, David O Willer, David H Evans In-fusion® cloning with vaccinia viru...
2012 Sophie Duraffour, Graciela Andrei, Dimitri Topalis, Marcela Krečmerová, Jean-Marc Crance, Daniel Garin, Robert Snoeck Mutations conferring resistance to vi...
2011 Kathleen A Boyle, Eleni S Stanitsa, Matthew D Greseth, Jill K Lindgren, Paula Traktman Evaluation of the role of the vaccini...
2009 Don B Gammon, David H Evans The 3'-to-5' exonuclease activity of ...
2008 Don B Gammon, Robert Snoeck, Pierre Fiten, Marcela Krecmerová, Antonín Holý, Erik De Clercq, Ghislain Opdenakker, David H Evans, Graciela Andrei Mechanism of antiviral drug resistanc...
2008 Wendy C Magee, Kathy A Aldern, Karl Y Hostetler, David H Evans Cidofovir and (S)-9-[3-hydroxy-(2-pho...
2007 Michael D Hamilton, Anthony A Nuara, Don B Gammon, R Mark Buller, David H Evans Duplex strand joining reactions catal...
2005 Wendy C Magee, Karl Y Hostetler, David H Evans Mechanism of inhibition of vaccinia v...
2005 Michael D Hamilton, David H Evans Enzymatic processing of replication a... 3-5' exo,5-3' exo,All properties
2001 A Punjabi, K Boyle, J DeMasi, O Grubisha, B Unger, M Khanna, P Traktman Clustered charge-to-alanine mutagenes...
2000 David O Willer, X D Yao, M J Mann, David H Evans In vitro concatemer formation catalyz...
1999 David O Willer, M J Mann, Weiming Zhang, David H Evans Vaccinia virus DNA polymerase promote...
1997 W F McDonald, N Klemperer, Paula Traktman Characterization of a processive form... Cloned or native,Full length or truncated,Processivity,3-5' exo,5-3' exo,Molecular Weight,Vmax,All properties
1994 W F McDonald, Paula Traktman Overexpression and purification of th...
1994 W F McDonald, Paula Traktman Vaccinia virus DNA polymerase. In vit...
1993 J A Taddie, Paula Traktman Genetic characterization of the vacci...
1992 W F McDonald, V Crozel-Goudot, Paula Traktman Transient expression of the vaccinia ...
1991 J A Taddie, Paula Traktman Genetic characterization of the vacci...
1984 F M Tomley, R J Cooper The DNA polymerase activity of vaccin...
1980 G Pedrali-Noy, Silvio Spadari Mechanism of inhibition of herpes sim...
1979 M D Challberg, Paul T Englund The effect of template secondary stru...
Protein sequence:
Name 3'-5' exo activity 5'-3' exo activity Frameshift Rate Substitution Rate General Error Rate
Vaccinia Virus Pol A314V
Vaccinia Virus Pol A314VA684V
Vaccinia Virus Pol T831I

Using Polbase tables:

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