Activation of a defective DNA polymerase in a temperature-sensitive mutant of bacteriophage T4.

Swartz MN, Nakamura H, Lehman IR
Virology (1972), Volume 47, Page 338
PubMed entry

Polymerases:

T4 A89TD363N,T4,T4 Q731am

Topics:

Mutational Analysis, Historical Protein Properties (MW, pI, ...), Modulators/Inhibitors, Kinetic Parameters, Nucleotide Incorporation, Enzyme Substrate Interactions

One line summary:

Inactive DNA polymerase formed at 43 degrees (Celsius) is reactivated upon lowering the temperature to 30 degrees.

Status:

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