Influence of amino acid deficiency and tRNA aminoacylation on DNA synthesis and DNA polymerase activity during the secondary immune response in vitro.
Abstract:
DNA synthesis and DNA polymerase activity are increased when KLH-primed guinea-pig lymphocytes are restimulated in vitro with the homologous antigen. This response can be modulated by glutamine deficiency and by an inhibitor of the histidyl-tRNA synthetase.
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new | topics/pols set | partial results | complete | validated |
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