[Security of dual cancer-specific targeting vector and its cytotoxic effect when harbored].

Wang J, Gu JF, Yang SY, Xiao T, Qi R, Sun LY, Liu XY
Ai zheng = Aizheng = Chinese journal of cancer (2006), Volume 25, Page 385
PubMed entry

Abstract:

The xenograft tumor mass in nude mice could be completely eliminated ...
The xenograft tumor mass in nude mice could be completely eliminated using the targeting dual gene-virotherapy strategy. Now, the most important point is to improve its security. This study was to construct dual cancer-specific targeting adenovirus called TD55 to evaluate its security, and construct TD55-TRAIL to explore its antitumor effect.

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