Selective inhibition of porcine endogenous retrovirus replication in human cells by acyclic nucleoside phosphonates.

Shi M, Wang X, De Clercq E, Takao S, Baba M
Antimicrobial agents and chemotherapy (2007), Volume 51, Page 2600
PubMed entry Full article text Publisher's site

Abstract:

Several anti-human immunodeficiency virus type 1 reverse transcriptase ...
Several anti-human immunodeficiency virus type 1 reverse transcriptase inhibitors were evaluated for their antiviral activities against porcine endogenous retrovirus in human cells. Among the test compounds, zidovudine was found to be the most active. The order of potency was zidovudine > phosphonylmethoxyethoxydiaminopyrimidine = phosphonylmethoxypropyldiaminopurine > tenofovir > or = adefovir > stavudine.

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