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Wallace SS

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Publications:

Title Authors Year Journal
Lesion bypass activity of DNA polymerase theta (POLQ) is an intrinsic property of the pol domain and depends on unique sequence inserts. Wallace SS 2011 Journal of molecular biology
A Crystallographic Study of the Role of Sequence Context in Thymine Glycol Bypass by a Replicative DNA Polymerase Serendipitously Sheds Light on the Exonuclease Complex. Wallace SS 2011 Journal of molecular biology
Kinetics of mismatch formation opposite lesions by the replicative DNA polymerase from bacteriophage RB69. Wallace SS 2010 Biochemistry
Crystal structure of a replicative DNA polymerase bound to the oxidized guanine lesion guanidinohydantoin. Wallace SS 2010 Biochemistry
Structural and biochemical investigation of the role in proofreading of a beta hairpin loop found in the exonuclease domain of a replicative DNA polymerase of the B family. Wallace SS 2007 The Journal of biological chemistry
A structural rationale for stalling of a replicative DNA polymerase at the most common oxidative thymine lesion, thymine glycol. Wallace SS 2007 Proceedings of the National Academy of Sciences of the United States of America
Caught bending the A-rule: crystal structures of translesion DNA synthesis with a non-natural nucleotide. Wallace SS 2007 Biochemistry
Kinetics of error generation in homologous B-family DNA polymerases. Wallace SS 2006 Nucleic acids research
Bumps in the road: how replicative DNA polymerases see DNA damage. Wallace SS 2005 Current opinion in structural biology
Crystallographic snapshots of a replicative DNA polymerase encountering an abasic site. Wallace SS 2004 The EMBO journal
Human DNA polymerase kappa bypasses and extends beyond thymine glycols during translesion synthesis in vitro, preferentially incorporating correct nucleotides. Wallace SS 2002 The Journal of biological chemistry
In vitro selection of sequence contexts which enhance bypass of abasic sites and tetrahydrofuran by T4 DNA polymerase holoenzyme. Wallace SS 1999 Journal of molecular biology
Enzymatic processing of uracil glycol, a major oxidative product of DNA cytosine. Wallace SS 1998 The Journal of biological chemistry
Uracil glycol deoxynucleoside triphosphate is a better substrate for DNA polymerase I Klenow fragment than thymine glycol deoxynucleoside triphosphate. Wallace SS 1998 Biochemistry
In search of a mutational hotspot. Wallace SS 1998 Proceedings of the National Academy of Sciences of the United States of America
5-Hydroxypyrimidine deoxynucleoside triphosphates are more efficiently incorporated into DNA by exonuclease-free Klenow fragment than 8-oxopurine deoxynucleoside triphosphates. Wallace SS 1994 Nucleic acids research
Absence of a role for DNA polymerase II in SOS-induced translesion bypass of phi X174. Wallace SS 1993 J Bacteriol
Processing of DNA base damage by DNA polymerases. Dihydrothymine and beta-ureidoisobutyric acid as models for instructive and noninstructive lesions. Wallace SS 1991 The Journal of biological chemistry
Dihydrothymidine and thymidine glycol triphosphates as substrates for DNA polymerases: differential recognition of thymine C5-C6 bond saturation and sequence specificity of incorporation. Wallace SS 1988 Nucleic acids research
Synthesis of dihydrothymidine and thymidine glycol 5'-triphosphates and their ability to serve as substrates for Escherichia coli DNA polymerase I. Wallace SS 1987 Biochemistry
Thymine glycols and urea residues in M13 DNA constitute replicative blocks in vitro. Wallace SS 1985 Nucleic acids research

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