DNA repair

(DNA Repair (Amst)) ISSNs: , 1568-7856

References in DNA repair:

Title Authors Year
Down-regulation of DNA polymerase beta accompanies somatic hypermutation in human BL2 cell lines. Poltoratsky VP, Prasad R, Horton JK, Wilson SH 2007
An intrinsic 5'-deoxyribose-5-phosphate lyase activity in DNA polymerase beta from Leishmania infantum supports a role in DNA repair. Alonso A, Terrados G, Picher AJ, Giraldo R, Blanco L, Larraga V 2006
Population-specific variation in haplotype composition and heterozygosity at the POLB locus. Yamtich J, Speed WC, Straka E, Kidd JR, Sweasy JB, Kidd KK 2009
DNA polymerase beta null mouse embryonic fibroblasts harbor a homozygous null mutation in DNA polymerase iota. Sobol RW 2007
A unique error signature for human DNA polymerase nu. Arana ME, Takata K, Garcia-Diaz M, Wood RD, Kunkel TA 2007
Structure-function studies of DNA polymerase lambda. Garcia-Diaz M, Bebenek K, Gao G, Pedersen LC, London RE, Kunkel TA 2005
DNA polymerase theta (POLQ) can extend from mismatches and from bases opposite a (6-4) photoproduct. Seki M, Wood RD 2008
DNA polymerase iota-dependent translesion replication of uracil containing cyclobutane pyrimidine dimers. Vaisman A, Takasawa K, Iwai S, Woodgate R 2006
How are specialized (low-fidelity) eukaryotic polymerases selected and switched with high-fidelity polymerases during translesion DNA synthesis? Fischhaber PL, Friedberg EC 2005
DNA polymerase beta and PARP activities in base excision repair in living cells. Masaoka A, Horton JK, Beard WA, Wilson SH 2009
Mgs1 and Rad18/Rad5/Mms2 are required for survival of Saccharomyces cerevisiae mutants with novel temperature/cold sensitive alleles of the DNA polymerase delta subunit, Pol31. Vijeh Motlagh ND, Seki M, Branzei D, Enomoto T 2006
On the role of proofreading exonuclease in bypass of a 1,2 d(GpG) cisplatin adduct by the herpes simplex virus-1 DNA polymerase. Arana ME, Song L, Tanguy Le Gac N, Parris DS, Villani G, Boehmer PE 2004
A nuclear 3'-5' exonuclease proofreads for the exonuclease-deficient DNA polymerase alpha. Brown KR, Weatherdon KL, Galligan CL, Skalski V 2002
Adenovirus mediated transduction of the human DNA polymerase eta cDNA. Lima-Bessa KM, Chiganças V, Stary A, Kannouche PL, Sarasin A, Armelini MG, de Fátima Jacysyn J, Amarante-Mendes GP, Cordeiro-Stone M, Cleaver JE, Menck CF 2006
Constitutive and regulated expression of the mouse Dinb (Polkappa) gene encoding DNA polymerase kappa. Velasco-Miguel S, Richardson JA, Gerlach VL, Lai WC, Gao T, Russell LD, Hladik CL, White CL, Friedberg EC 2003
The influence of the DNA polymerase gamma accessory subunit on base excision repair by the catalytic subunit. Pinz KG, Bogenhagen DF 2006
UV-induced RPA phosphorylation is increased in the absence of DNA polymerase eta and requires DNA-PK. Cruet-Hennequart S, Coyne S, Glynn MT, Oakley GG, Carty MP 2006
Biochemical studies with DNA polymerase beta and DNA polymerase beta-PAK of Trypanosoma cruzi suggest the involvement of these proteins in mitochondrial DNA maintenance. Lopes Dde O, Schamber-Reis BL, Regis-da-Silva CG, Rajão MA, DaRocha WD, Macedo AM, Franco GR, Nardelli SC, Schenkman S, Hoffmann JS, Cazaux C, Pena SD, Teixeira SM, Machado CR 2008
DNA polymerase beta is critical for genomic stability of sperm cells. Kidane D, Dalal S, Keh A, Liu Y, Zelterman D, Sweasy JB 2011
Lesion bypass by S. cerevisiae Pol ζ alone. Stone JanaE, Kumar Dinesh, Binz SaraK, Inase Aki, Iwai Shigenori, Chabes Andrei, Burgers PeterM, Kunkel ThomasA 2011
Bypass of N²-ethylguanine by human DNA polymerase κ. Pence MG, Blans P, Zink CN, Fishbein JC, Perrino FW 2011
The murine DNA glycosylase NEIL2 (mNEIL2) and human DNA polymerase beta bind microtubules in situ and in vitro. Conlon KA, Miller H, Rosenquist TA, Zharkov DO, Berrios M 2005
The in vitro fidelity of yeast DNA polymerase δ and polymerase ε holoenzymes during dinucleotide microsatellite DNA synthesis. Abdulovic AL, Hile SE, Kunkel TA, Eckert KA 2011
Mismatch repair-independent tandem repeat sequence instability resulting from ribonucleotide incorporation by DNA polymerase ε. Clark AB, Lujan SA, Kissling GE, Kunkel TA 2011
DNA polymerase beta-dependent long patch base excision repair in living cells. Asagoshi K, Liu Y, Masaoka A, Lan L, Prasad R, Horton JK, Brown AR, Wang XH, Bdour HM, Sobol RW, Taylor JS, Yasui A, Wilson SH 2010
Regulated over-expression of DNA polymerase beta mediates early onset cataract in mice. Sobol RW, Foley JF, Nyska A, Davidson MG, Wilson SH 2003
Aphidicolin-resistant and -sensitive base excision repair in wild-type and DNA polymerase beta-defective mouse cells. Parlanti E, Pascucci B, Terrados G, Blanco L, Dogliotti E 2004
The overexpression of specialized DNA polymerases in cancer. Albertella MR, Lau A, O'Connor MJ 2005
Hypersensitivity of DNA polymerase beta null mouse fibroblasts reflects accumulation of cytotoxic repair intermediates from site-specific alkyl DNA lesions. Horton JK, Joyce-Gray DF, Pachkowski BF, Swenberg JA, Wilson SH 2003
p53 suppression overwhelms DNA polymerase eta deficiency in determining the cellular UV DNA damage response. Laposa RR, Feeney L, Crowley E, de Feraudy S, Cleaver JE 2007
Loop II of DNA polymerase beta is important for discrimination during substrate binding. Lin GC, Jaeger J, Eckert KA, Sweasy JB 2009
A role for DNA polymerase V in G --> T mutations from the major benzo[a]pyrene N2-dG adduct when studied in a 5'-TGT sequence in E. coli. Yin J, Seo KY, Loechler EL 2004
Sequence context-dependent replication of DNA templates containing UV-induced lesions by human DNA polymerase iota. Vaisman A, Frank EG, Iwai S, Ohashi E, Ohmori H, Hanaoka F, Woodgate R 2003
Activities of human DNA polymerase kappa in response to the major benzo[a]pyrene DNA adduct: error-free lesion bypass and extension synthesis from opposite the lesion. Zhang Y, Wu X, Guo D, Rechkoblit O, Wang Z 2002
Lack of DNA polymerase mu affects the kinetics of DNA double-strand break repair and impacts on cellular senescence. Chayot R, Danckaert A, Montagne B, Ricchetti M 2010
Cellular roles of DNA polymerase zeta and Rev1 protein. Lawrence CW 2002
Mutability of DNA polymerase I: implications for the creation of mutant DNA polymerases. Loh E, Loeb LA 2005
'Knock down' of DNA polymerase beta by RNA interference: recapitulation of null phenotype. Polosina YY, Rosenquist TA, Grollman AP, Miller H 2004
Analysis of translesion replication across an abasic site by DNA polymerase IV of Escherichia coli. Maor-Shoshani A, Hayashi K, Ohmori H, Livneh Z 2003
Co-localization in replication foci and interaction of human Y-family members, DNA polymerase pol eta and REVl protein. Tissier A, Kannouche PL, Reck MP, Lehmann AR, Fuchs RP, Cordonnier A 2004
Involvement of DNA polymerase beta in protection against the cytotoxicity of oxidative DNA damage. Horton JK, Baker A, Berg BJ, Sobol RW, Wilson SH 2002
Functions of human DNA polymerases eta, kappa and iota suggested by their properties, including fidelity with undamaged DNA templates. Kunkel TA, Pavlov YI, Bebenek K 2003
Identification of specific amino acid residues in the E. coli beta processivity clamp involved in interactions with DNA polymerase III, UmuD and UmuD'. Duzen JM, Walker GC, Sutton MD 2004
Structure-based interpretation of missense mutations in Y-family DNA polymerases and their implications for polymerase function and lesion bypass. Boudsocq F, Ling H, Yang WW, Woodgate R 2002
The X family portrait: structural insights into biological functions of X family polymerases. Moon AF, Garcia-Diaz M, Batra VK, Beard WA, Bebenek K, Kunkel TA, Wilson SH, Pedersen LC 2007
Replication of 2-hydroxyadenine-containing DNA and recognition by human MutSalpha. Barone F, McCulloch SD, Macpherson P, Maga G, Yamada M, Nohmi T, Minoprio A, Mazzei F, Kunkel TA, Karran P, Bignami M 2007
Catalytic mechanism of human DNA polymerase lambda with Mg2+ and Mn2+ from ab initio quantum mechanical/molecular mechanical studies. Cisneros GA, Perera L, García-Díaz M, Bebenek K, Kunkel TA, Pedersen LG 2008
Interaction with DNA polymerase eta is required for nuclear accumulation of REV1 and suppression of spontaneous mutations in human cells. Akagi JI, Masutani C, Kataoka Y, Kan T, Ohashi E, Mori T, Ohmori H, Hanaoka F 2009
Overproduction of DNA polymerase eta does not raise the spontaneous mutation rate in diploid human fibroblasts. King NM, Nikolaishvili-Feinberg N, Bryant MF, Luche DD, Heffernan TP, Simpson DA, Hanaoka F, Kaufmann WK, Cordeiro-Stone M 2005
Role of the catalytic metal during polymerization by DNA polymerase lambda. Garcia-Diaz M, Bebenek K, Krahn JM, Pedersen LC, Kunkel TA 2007
Functions of base selection step in human DNA polymerase alpha. Tanaka S, Cao K, Niimi A, Limsirichaikul S, Miao HQ, Nakamura N, Murate T, Hasegawa Y, Takahashi T, Suzuki M 2010
Multiple solutions to inefficient lesion bypass by T7 DNA polymerase. McCulloch SD, Kunkel TA 2006
Mechanisms by which herpes simplex virus DNA polymerase limits translesion synthesis through abasic sites. Zhu Y, Song L, Stroud J, Parris DS 2008
Intrinsic 5'-deoxyribose-5-phosphate lyase activity in Saccharomyces cerevisiae Trf4 protein with a possible role in base excision DNA repair. Gellon L, Carson DR, Carson JP, Demple B 2008
Structural insight into the DNA polymerase beta deoxyribose phosphate lyase mechanism. Prasad R, Batra VK, Yang XP, Krahn JM, Pedersen LC, Beard WA, Wilson SH 2005
Ischemic preconditioning induces XRCC1, DNA polymerase-beta, and DNA ligase III and correlates with enhanced base excision repair. Li N, Wu H, Yang S, Chen D 2007
Mitochondrial DNA integrity is not dependent on DNA polymerase-beta activity. Hansen AB, Griner NB, Anderson JP, Kujoth GC, Prolla TA, Loeb LA, Glick E 2006
Human DNA polymerase lambda is a proficient extender of primer ends paired to 7,8-dihydro-8-oxoguanine. Picher AJ, Blanco L 2007
Specific amino acid residues in the beta sliding clamp establish a DNA polymerase usage hierarchy in Escherichia coli. Sutton MD, Duzen JM 2006
Participation of DNA polymerase II in the increased precise excision of Tn10. Nagel R, Chan A 2003
Reduced efficiency and increased mutagenicity of translesion DNA synthesis across a TT cyclobutane pyrimidine dimer, but not a TT 6-4 photoproduct, in human cells lacking DNA polymerase eta. Hendel A, Ziv O, Gueranger Q, Geacintov NE, Livneh Z 2008
The role of DNA polymerase eta in UV mutational spectra. Choi JH, Pfeifer GP 2005
Specificity of mutations induced by incorporation of oxidized dNTPs into DNA by human DNA polymerase eta. Hidaka K, Yamada M, Kamiya H, Masutani C, Harashima H, Hanaoka F, Nohmi T 2008
Altered translesion synthesis in E. coli Pol V mutants selected for increased recombination inhibition. Sommer S, Becherel OJ, Coste G, Bailone A, Fuchs RP 2003
Role for DNA polymerase beta in response to ionizing radiation. Vermeulen C, Verwijs-Janssen M, Cramers P, Begg AC, Vens C 2007
Stable interactions between DNA polymerase delta catalytic and structural subunits are essential for efficient DNA repair. Brocas C, Charbonnier JB, Dhérin C, Gangloff S, Maloisel L 2010
Mono-allelic POLG expression resulting from nonsense-mediated decay and alternative splicing in a patient with Alpers syndrome. Chan SS, Longley MJ, Naviaux RK, Copeland WC 2005
Human DNA polymerase λ catalyzes lesion bypass across benzo[a]pyrene-derived DNA adduct during base excision repair. Skosareva LV, Lebedeva NA, Rechkunova NI, Kolbanovskiy A, Geacintov NE, Lavrik OI 2012
A comparison of BRCT domains involved in nonhomologous end-joining: introducing the solution structure of the BRCT domain of polymerase lambda. Mueller GA, Moon AF, DeRose EF, Havener JM, Ramsden DA, Pedersen LC, London RE 2008
REV1 mediated mutagenesis in base excision repair deficient mouse fibroblast. Poltoratsky VP, Horton JK, Prasad R, Wilson SH 2005
Genetic analysis reveals an intrinsic property of the germinal center B cells to generate A:T mutations. Ouchida R, Ukai A, Mori H, Kawamura K, Dollé ME, Tagawa M, Sakamoto A, Tokuhisa T, Yokosuka T, Saito T, Yokoi M, Hanaoka F, Vijg J, Wang JY 2008
Base excision repair in nucleosomes lacking histone tails. Beard BC, Stevenson JJ, Wilson SH, Smerdon MJ 2005
Interplay between DNA polymerases beta and lambda in repair of oxidation DNA damage in chicken DT40 cells. Tano K, Nakamura J, Asagoshi K, Arakawa H, Sonoda E, Braithwaite EK, Prasad R, Buerstedde JM, Takeda S, Watanabe M, Wilson SH 2007
Hypersensitivity phenotypes associated with genetic and synthetic inhibitor-induced base excision repair deficiency. Horton JK, Wilson SH 2007
NEIL2-initiated, APE-independent repair of oxidized bases in DNA: Evidence for a repair complex in human cells. Das A, Wiederhold L, Leppard JB, Kedar PS, Prasad R, Wang H, Boldogh I, Karimi-Busheri F, Weinfeld M, Tomkinson AE, Wilson SH, Mitra S, Hazra TK 2006
Reevaluation of the role of DNA polymerase theta in somatic hypermutation of immunoglobulin genes. Martomo SA, Saribasak H, Yokoi M, Hanaoka F, Gearhart PJ 2008
Involvement of poly(ADP-ribose) polymerase activity in regulating Chk1-dependent apoptotic cell death. Horton JK, Stefanick DF, Wilson SH 2005
Normal hypermutation in antibody genes from congenic mice defective for DNA polymerase iota. Martomo SA, Yang WW, Vaisman A, Maas A, Yokoi M, Hoeijmakers JH, Hanaoka F, Woodgate R, Gearhart PJ 2006
AP endonuclease and poly(ADP-ribose) polymerase-1 interact with the same base excision repair intermediate. Cistulli C, Lavrik OI, Prasad R, Hou EW, Wilson SH 2004
Mutator alleles of yeast DNA polymerase zeta. Sakamoto AN, Stone JE, Kissling GE, McCulloch SD, Pavlov YI, Kunkel TA 2007
Role of DNA polymerases eta, iota and zeta in UV resistance and UV-induced mutagenesis in a human cell line. Gueranger Quentin, Stary Anne, Aoufouchi Saïd, Faili Ahmad, Sarasin Alain, Reynaud Claude-Agnès, Weill Jean-Claude 2008
Lyase activities intrinsic to Escherichia coli polymerases IV and V. Shen X, Woodgate R, Goodman MF 2005
Insights into the cellular role of enigmatic DNA polymerase iota. Vidal AE, Woodgate R 2009
Construction of a circular single-stranded DNA template containing a defined lesion. Karata K, Vidal AE, Woodgate R 2009
Ddc1 checkpoint protein and DNA polymerase ɛ interact with nick-containing DNA repair intermediate in cell free extracts of Saccharomyces cerevisiae. Sukhanova MV, D'Herin C, van der Kemp PA, Koval VV, Boiteux S, Lavrik OI 2011
Efficiency and fidelity of human DNA polymerases λ and β during gap-filling DNA synthesis. Brown JA, Pack LR, Sanman LE, Suo Z 2011
Mutational clusters generated by non-processive polymerases: A case study using DNA polymerase betain vitro. García-Villada L, Drake JW 2010
Oxygen as a friend and enemy: How to combat the mutational potential of 8-oxo-guanine. van Loon B, Markkanen E, Hübscher U 2010
The intricate structural chemistry of base excision repair machinery: implications for DNA damage recognition, removal, and repair. Hitomi K, Iwai S, Tainer JA 2007
Involvement of specialized DNA polymerases in mutagenesis by 8-hydroxy-dGTP in human cells. Satou Kazuya, Hori Mika, Kawai Kazuaki, Kasai Hiroshi, Harashima Hideyoshi, Kamiya Hiroyuki 2009
Proofreading of ribonucleotides inserted into DNA by yeast DNA polymerase ɛ Williams JS, Clausen AR, Nick McElhinny SA, Watts BE, Johansson E, Kunkel TA 2012
DNA polymerase eta is targeted by Mdm2 for polyubiquitination and proteasomal degradation in response to ultraviolet irradiation. Jung YS, Qian Y, Chen X 2012
Simple and efficient purification of Escherichia coli DNA polymerase V: Cofactor requirements for optimal activity and processivity in vitro. Karata K, Vaisman A, Goodman MF, Woodgate R 2012
Escherichia coli UmuC active site mutants: Effects on translesion DNA synthesis, mutagenesis and cell survival. Kuban W, Vaisman A, McDonald JP, Karata K, Yang WW, Goodman MF, Woodgate R 2012
Roles of the Y-family DNA polymerase Dbh in accurate replication of the Sulfolobus genome at high temperature. Sakofsky CJ, Foster PL, Grogan DW 2012
DNA polymerase μ is a global player in the repair of non-homologous end-joining substrates. Chayot R, Montagne B, Ricchetti M 2012
Ribonucleotide incorporation, proofreading and bypass by human DNA polymerase δ Clausen AR, Zhang S, Burgers PM, Lee MY, Kunkel TA 2012
Exonuclease 1 preferentially repairs mismatches generated by DNA polymerase α Liberti SE, Larrea AA, Kunkel TA 2012
Mouse DNA polymerase kappa has a functional role in the repair of DNA strand breaks. Zhang X, Lv L, Chen Q, Yuan F, Zhang T, Yang Y, Zhang H, Wang Y, Jia Y, Qian L, Chen B, Zhang Y, Friedberg EC, Tang TS, Guo C 2013
The role of the PHP domain associated with DNA polymerase X from Thermus thermophilus HB8 in base excision repair. Nakane S, Nakagawa N, Kuramitsu S, Masui R 2012
Specificity of replicative and SOS-inducible DNA polymerases in frameshift mutagenesis: mutability of Salmonella typhimurium strains overexpressing SOS-inducible DNA polymerases to 30 chemical mutagens. Matsui K, Yamada M, Imai M, Yamamoto K, Nohmi T 2006
Roles of replicative and specialized DNA polymerases in frameshift mutagenesis: mutability of Salmonella typhimurium strains lacking one or all of SOS-inducible DNA polymerases to 26 chemicals. Kokubo K, Yamada M, Kanke Y, Nohmi T 2005
Preventing oxidation of cellular XRCC1 affects PARP-mediated DNA damage responses. Horton JK, Stefanick DF, Gassman NR, Williams JG, Gabel SA, Cuneo MJ, Prasad R, Kedar PS, DeRose EF, Hou EW, London RE, Wilson SH 2013
DNA polymerase POLQ and cellular defense against DNA damage. Yousefzadeh MJ, Wood RD 2013
The human gastric cancer-associated DNA polymerase β variant D160N is a mutator that induces cellular transformation. Donigan KA, Hile SE, Eckert KA, Sweasy JB 2012
Dynamics of enzymatic interactions during short flap human Okazaki fragment processing by two forms of human DNA polymerase δ Lin SH, Wang X, Zhang S, Zhang Z, Lee EY, Lee MY 2013
PCNA trimer instability inhibits translesion synthesis by DNA polymerase η and by DNA polymerase δ. Dieckman LM, Washington MT 2013
The mechanism of human tyrosyl-DNA phosphodiesterase 1 in the cleavage of AP site and its synthetic analogs. Lebedeva NA, Rechkunova NI, Ishchenko AA, Saparbaev M, Lavrik OI 2013
Replication of ribonucleotide-containing DNA templates by yeast replicative polymerases. Watt DL, Johansson E, Burgers PM, Kunkel TA 2011
In vivo evidence that phenylalanine 171 acts as a molecular brake for translesion DNA synthesis across benzo[a]pyrene DNA adducts by human DNA polymerase κ. Sassa A, Suzuki T, Kanemaru Y, Niimi N, Fujimoto H, Katafuchi A, Grúz P, Yasui M, Gupta RC, Johnson F, Ohta T, Honma M, Adachi N, Nohmi T 2014
The excision of 3' penultimate errors by DNA polymerase I and its role in endonuclease V-mediated DNA repair. Lee CC, Yang YC, Goodman SD, Lin CJ, Chen YA, Wang YT, Cheng WC, Lin LI, Fang WH 2013
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DNA polymerase 3'→5' exonuclease activity: Different roles of the beta hairpin structure in family-B DNA polymerases. Darmawan H, Harrison M, Reha-Krantz LJ 2015

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