Human Pol nu

From H. sapiens (aliases:POLN, POL4P) (genes: POLN)
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Welcome to the Polymerase Page

This page presents all the information in Polbase for Human Pol nu.

Mutants:

At the top of the page you'll find a map of all positions of known mutants. Text links to mutants and digestion products are listed in the Mutants section.

Structures/Sequence:

If available, a representative structure is displayed at the upper right. All known structures are listed in the Structures section.

External links:

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References:

All references that refer to this Polymerase are listed with their topics and paper's title in the References table.

Results:

All the results for this polymerase can be examined by following the "Results" link at the bottom of the page.

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Human Pol nu is a family A enzyme from H. sapiens.

Selected Properties for Human Pol nu:

 3'-5' exo activity 5'-3' exo activity Frameshift Rate Substitution Rate General Error Rate
No (2) no data no data 3.5e-03 errors/bp (1) no data
Year Authors Title Results by property
2011 Mercedes E Arana, Olga Potapova, Thomas A Kunkel, Catherine M Joyce Kinetic analysis of the unique error ...
2010 Kei-ichi Takata, Mercedes E Arana, Masayuki Seki, Thomas A Kunkel, Richard D Wood Evolutionary conservation of residues...
2010 Mercedes E Arana, Gary K Powell, Lori L Edwards, Thomas A Kunkel, Robert M Petrovich Refolding active human DNA polymerase...
2010 Mark D Sutton Coordinating DNA polymerase traffic d...
2009 Laura Zietlow, Leigh Anne Smith, Mika Bessho, Tadayoshi Bessho Evidence for the involvement of human...
2007 Mercedes E Arana, Kei-ichi Takata, Miguel Garcia-Diaz, Richard D Wood, Thomas A Kunkel A unique error signature for human DN... Cloned or native,Tagged,Tag Name,3-5' exo,Nucleotide Substitution Rate,All properties
2006 Kei-ichi Takata, Tatsuhiko Shimizu, Shigenori Iwai, Richard D Wood Human DNA polymerase N (POLN) is a lo... Processivity,Nick Extension,Strand Displacement,3-5' exo,Molecular Weight,Amino Acids Contacting NTP,Template lesions,All properties

Version:20241007

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