On the role of deoxyribonucleic acid polymerase in determining mutation rates. Characterization of the defect in the T4 deoxyribonucleic acid polymerase caused by the ts L88 mutation.

Hershfield MS
The Journal of biological chemistry (1973), Volume 248, Page 1417
PubMed entry

Polymerases:

T4

Topics:

Fidelity, Nucleotide Incorporation, Exonuclease Activity, Source / Purification

One line summary:

The tsL88 (G694S) DNA polymerase had reduced accuracy of nucleotide incorporation.

Status:

new topics/pols set partial results complete validated

Results:

Polymerase Reference Property Result Context
T4 On the role of deoxyribonucleic acid polymerase in determining mutation rates. Characterization of the defect in the T4 deoxyribonucleic acid polymerase caused by the ts L88 mutation. 3-5' Exonuclease (proofreading) Yes
T4 On the role of deoxyribonucleic acid polymerase in determining mutation rates. Characterization of the defect in the T4 deoxyribonucleic acid polymerase caused by the ts L88 mutation. Cloned or native Native organism
T4 On the role of deoxyribonucleic acid polymerase in determining mutation rates. Characterization of the defect in the T4 deoxyribonucleic acid polymerase caused by the ts L88 mutation. Tagged No
T4 On the role of deoxyribonucleic acid polymerase in determining mutation rates. Characterization of the defect in the T4 deoxyribonucleic acid polymerase caused by the ts L88 mutation. Full length or truncated Full length
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Version:20241218

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