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A low molecular weight DNA polymerase from ovaries of the frog Xenopus laevis. DNA polymerase-beta (ovarian). |
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Aphidicolin, a specific inhibitor of DNA polymerase alpha, inhibits conversion of lanosterol to C-27 sterols in mouse L cells. |
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Two Epstein-Barr virus-associated DNA polymerase activities. |
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Size classes of products synthesized processively by two subassemblies of Escherichia coli DNA polymerase III holoenzyme. |
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Selective oxidation of the exonuclease domain of bacteriophage T7 DNA polymerase. |
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The development and use of a DNA polymerase arrest assay for the evaluation of parameters affecting intrastrand tetraplex formation. |
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The use of Taq DNA polymerase to determine the sequence specificity of DNA damage caused by cis-diamminedichloroplatinum(II), acridine-tethered platinum(II) diammine complexes or two analogues. |
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Fluorescence energy transfer between the primer and the beta subunit of the DNA polymerase III holoenzyme. |
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DNA polymerase III holoenzyme. Components, structure, and mechanism of a true replicative complex. |
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Specificity and enzymatic mechanism of the editing exonuclease of Escherichia coli DNA polymerase III. |
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Functional human mitochondrial DNA polymerase gamma forms a heterotrimer. |
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Herpes simplex virus type 1 and human DNA polymerase interactions with 2'-deoxyguanosine 5'-triphosphate analogues. Kinetics of incorporation into DNA and induction of inhibition. |
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Mutational studies of human DNA polymerase alpha. Lysine 950 in the third most conserved region of alpha-like DNA polymerases is involved in binding the deoxynucleoside triphosphate. |
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3'-->5' exonuclease active site of phi 29 DNA polymerase. Evidence favoring a metal ion-assisted reaction mechanism. |
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A new DNA-dependent ATPase which stimulates yeast DNA polymerase I and has DNA-unwinding activity. |
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Persistence of deoxyribonucleic acid polymerase I and its 5'--3' exonuclease activity in PolA mutants of Escherichia coli K12. |
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Crystal structure of epstein-barr virus DNA polymerase processivity factor BMRF1. |
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Purification and characterization of bacteriophage N4-induced DNA polymerase. |
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Mouse DNA polymerase alpha. Subunit structure and identification of a species with associated exonuclease. |
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The effect of template secondary structure on vaccinia DNA polymerase. |
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DNA polymerase-alpha. Purification and structural characterization of the near homogeneous enzyme from human KB cells. |
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Modulation of the structure, catalytic activity, and fidelity of African swine fever virus DNA polymerase X by a reversible disulfide switch. |
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GINS is a DNA polymerase epsilon accessory factor during chromosomal DNA replication in budding yeast. |
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Initiation of new DNA strands by the herpes simplex virus-1 primase-helicase complex and either herpes DNA polymerase or human DNA polymerase alpha. |
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Purification and characterization of a DNA polymerase beta from Drosophila*. |
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A conserved Hsp10-like domain in Mcm10 is required to stabilize the catalytic subunit of DNA polymerase-alpha in budding yeast. |
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Kinetic evidence for inefficient and error-prone bypass across bulky N2-guanine DNA adducts by human DNA polymerase iota. |
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The highly processive DNA polymerase of bacteriophage T5. Role of the unique N and C termini. |
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DNA polymerase III holoenzyme of Escherichia coli. Purification and resolution into subunits. |
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Subunit interaction and regulation of activity through terminal domains of the family D DNA polymerase from Pyrococcus horikoshii. |
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Role of DNA polymerase eta in the UV mutation spectrum in human cells. |
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Identification of a novel protein, PDIP38, that interacts with the p50 subunit of DNA polymerase delta and proliferating cell nuclear antigen. |
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2003 |
Mechanism of loading the Escherichia coli DNA polymerase III beta sliding clamp on DNA. Bona fide primer/templates preferentially trigger the gamma complex to hydrolyze ATP and load the clamp. |
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2003 |
Weak strand displacement activity enables human DNA polymerase beta to expand CAG/CTG triplet repeats at strand breaks. |
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Contacts between the 5' nuclease of DNA polymerase I and its DNA substrate. |
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A three-domain structure for the delta subunit of the DNA polymerase III holoenzyme delta domain III binds delta' and assembles into the DnaX complex. |
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Covalent trapping of human DNA polymerase beta by the oxidative DNA lesion 2-deoxyribonolactone. |
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Resolving a fidelity paradox: why Escherichia coli DNA polymerase II makes more base substitution errors in AT- compared with GC-rich DNA. |
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Chromodomain protein Swi6-mediated role of DNA polymerase alpha in establishment of silencing in fission Yeast. |
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Mismatch extension ability of yeast and human DNA polymerase eta. |
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Secondary structure and structure-activity relationships of peptides corresponding to the subunit interface of herpes simplex virus DNA polymerase. |
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The E249K mutator mutant of DNA polymerase beta extends mispaired termini. |
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Isolation and characterization of a split B-type DNA polymerase from the archaeon Methanobacterium thermoautotrophicum deltaH. |
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Mismatch extension by Escherichia coli DNA polymerase III holoenzyme. |
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Human DNA polymerase beta deoxyribose phosphate lyase. Substrate specificity and catalytic mechanism. |
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Accessory subunit of mitochondrial DNA polymerase from Drosophila embryos. Cloning, molecular analysis, and association in the native enzyme. |
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Pre-steady state analysis of the assembly of wild type and mutant circular clamps of Escherichia coli DNA polymerase III onto DNA. |
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The Escherichia coli polB locus is identical to dinA, the structural gene for DNA polymerase II. Characterization of Pol II purified from a polB mutant. |
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Mutational studies of human DNA polymerase alpha. Serine 867 in the second most conserved region among alpha-like DNA polymerases is involved in primer binding and mispair primer extension. |
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DNA polymerase alpha overcomes an error-prone pause site in the presence of replication protein-A. |
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Adenovirus DNA polymerase is a phosphoprotein. |
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Evidence that an archaeal alpha-like DNA polymerase has a modular organization of its associated catalytic activities. |
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Interaction of proliferating cell nuclear antigen with yeast DNA polymerase delta. |
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Structural relationships between two forms of DNA polymerase epsilon from calf thymus. |
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1992 |
Immunoaffinity-purified DNA polymerase alpha from a mouse temperature-sensitive mutant, tsFT20 strain, is heat-labile. |
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DNA polymerase lambda mediates a back-up base excision repair activity in extracts of mouse embryonic fibroblasts. |
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The block of DNA polymerase delta strand displacement activity by an abasic site can be rescued by the concerted action of DNA polymerase beta and Flap endonuclease 1. |
Maga G, van Loon B, Crespan E, Villani G, Hübscher U |
2009 |
Biochemical basis of genotoxicity of heterocyclic arylamine food mutagens: Human DNA polymerase eta selectively produces a two-base deletion in copying the N2-guanyl adduct of 2-amino-3-methylimidazo[4,5-f]quinoline but not the C8 adduct at the NarI G3 site. |
Choi JY, Stover JS, Angel KC, Chowdhury G, Rizzo CJ, Guengerich FP |
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Site-directed mutations of T4 helicase loading protein (gp59) reveal multiple modes of DNA polymerase inhibition and the mechanism of unlocking by gp41 helicase. |
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2006 |
Mammalian translesion DNA synthesis across an acrolein-derived deoxyguanosine adduct. Participation of DNA polymerase eta in error-prone synthesis in human cells. |
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2003 |
Threonine 79 is a hinge residue that governs the fidelity of DNA polymerase beta by helping to position the DNA within the active site. |
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DNA polymerase lambda from calf thymus preferentially replicates damaged DNA. |
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Preferential misincorporation of purine nucleotides by human DNA polymerase eta opposite benzo[a]pyrene 7,8-diol 9,10-epoxide deoxyguanosine adducts. |
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Fidelity and damage bypass ability of Schizosaccharomyces pombe Eso1 protein, comprised of DNA polymerase eta and sister chromatid cohesion protein Ctf7. |
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2001 |
Carboxyl-terminal domain III of the delta' subunit of the DNA polymerase III holoenzyme binds delta. |
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2001 |
Multiple phosphorylation sites of DNA polymerase alpha-primase cooperate to regulate the initiation of DNA replication in vitro. |
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Identification of an intrinsic 5'-deoxyribose-5-phosphate lyase activity in human DNA polymerase lambda: a possible role in base excision repair. |
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Transcriptional regulation of the human DNA polymerase delta catalytic subunit gene POLD1 by p53 tumor suppressor and Sp1. |
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Differential incorporation and removal of antiviral deoxynucleotides by human DNA polymerase gamma. |
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A complex of the bacteriophage T7 primase-helicase and DNA polymerase directs primer utilization. |
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2001 |
Lesion bypass by the Escherichia coli DNA polymerase V requires assembly of a RecA nucleoprotein filament. |
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2001 |
FEN1 stimulation of DNA polymerase beta mediates an excision step in mammalian long patch base excision repair. |
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3'-Azido-3'-deoxythymidine-resistant mutants of DNA polymerase beta identified by in vivo selection. |
Kosa JL, Sweasy JB |
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Strand asymmetry of +1 frameshift mutagenesis at a homopolymeric run by DNA polymerase III holoenzyme of Escherichia coli. |
Seki M, Akiyama MT, Sugaya Y, Ohtsubo E, Maki H |
1999 |
Analysis of strand slippage in DNA polymerase expansions of CAG/CTG triplet repeats associated with neurodegenerative disease. |
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Architecture of the active DNA polymerase delta.proliferating cell nuclear antigen.template-primer complex. |
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Role of the putative zinc finger domain of Saccharomyces cerevisiae DNA polymerase epsilon in DNA replication and the S/M checkpoint pathway. |
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A smaller form of the sliding clamp subunit of DNA polymerase III is induced by UV irradiation in Escherichia coli. |
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Characterization of the p125 subunit of human DNA polymerase delta and its deletion mutants. Interaction with cyclin-dependent kinase-cyclins. |
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Structural analyses of gp45 sliding clamp interactions during assembly of the bacteriophage T4 DNA polymerase holoenzyme. I. Conformational changes within the gp44/62-gp45-ATP complex during clamp loading. |
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Dissociation of the protein primer and DNA polymerase after initiation of adenovirus DNA replication. |
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Effects of Xenopus laevis mitochondrial single-stranded DNA-binding protein on primer-template binding and 3'-->5' exonuclease activity of DNA polymerase gamma. |
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Abasic translesion synthesis by DNA polymerase beta violates the "A-rule". Novel types of nucleotide incorporation by human DNA polymerase beta at an abasic lesion in different sequence contexts. |
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Pyridoxal 5'-phosphate inhibition of adenovirus DNA polymerase. |
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DNA replication-related elements cooperate to enhance promoter activity of the drosophila DNA polymerase alpha 73-kDa subunit gene. |
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Phorbol ester abrogates up-regulation of DNA polymerase beta by DNA-alkylating agents in Chinese hamster ovary cells. |
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Structural and functional organization of herpes simplex virus DNA polymerase investigated by limited proteolysis. |
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Identification of residues in the single-stranded DNA-binding site of the 8-kDa domain of rat DNA polymerase beta by UV cross-linking. |
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Mutational analysis of the human DNA polymerase alpha. The most conserved region in alpha-like DNA polymerases is involved in metal-specific catalysis. |
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Poly(ADP-ribose) polymerase stimulates DNA polymerase alpha by physical association. |
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Interactions of gene 2.5 protein and DNA polymerase of bacteriophage T7. |
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Purification of a mitochondrial DNA polymerase from Crithidia fasciculata. |
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Constitution of the twin polymerase of DNA polymerase III holoenzyme. |
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Modular organization of T4 DNA polymerase. Evidence from phylogenetics. |
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A single mutation in human mitochondrial DNA polymerase Pol gammaA affects both polymerization and proofreading activities of only the holoenzyme. |
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Formation of a DNA loop at the replication fork generated by bacteriophage T7 replication proteins. |
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Sequence requirements for protein-primed initiation and elongation of phage O29 DNA replication. |
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Truncating alpha-helix E' of p66 human immunodeficiency virus reverse transcriptase modulates RNase H function and impairs DNA strand transfer. |
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Characterization of the helicase and primase activities of the 63-kDa component of the bacteriophage T7 gene 4 protein. |
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Effects of aphidicolin and/or 2',3'-dideoxythymidine on DNA repair induced in HeLa cells by four types of DNA-damaging agents. |
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Leading and lagging strand synthesis at the replication fork of bacteriophage T7. Distinct properties of T7 gene 4 protein as a helicase and primase. |
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Priming of deoxyribonucleic acid synthesis on phage fd and phiX174 templates by oligoribonucleotides contaminating nucleoside 5'-triphosphates. |
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Tau binds and organizes Escherichia coli replication proteins through distinct domains. Domain III, shared by gamma and tau, binds delta delta ' and chi psi. |
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Selective inhibition of HIV-1 reverse transcriptase by an antiviral inhibitor, (R)-9-(2-Phosphonylmethoxypropyl)adenine. |
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Incorporation and replication of 8-oxo-deoxyguanosine by the human mitochondrial DNA polymerase. |
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Characterization of novel reverse transcriptase and other RNA-associated catalytic activities by human DNA polymerase gamma: importance in mitochondrial DNA replication. |
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Role of induced fit in enzyme specificity: a molecular forward/reverse switch. |
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