DNA Polymerase λ Inactivation by Oxidized Abasic Sites.
|
Kunkel TA
|
2013
|
Biochemistry
|
DNA polymerase δ stalls on telomeric lagging strand templates independently from G-quadruplex formation.
|
Kunkel TA
|
2013
|
Nucleic acids research
|
Exonuclease 1 preferentially repairs mismatches generated by DNA polymerase α
|
Kunkel TA
|
2012
|
DNA repair
|
The catalytic cycle for ribonucleotide incorporation by human DNA Pol λ
|
Kunkel TA
|
2012
|
Nucleic acids research
|
Proofreading of ribonucleotides inserted into DNA by yeast DNA polymerase ɛ
|
Kunkel TA
|
2012
|
DNA repair
|
RNase H2-Initiated Ribonucleotide Excision Repair.
|
Kunkel TA
|
2012
|
Molecular cell
|
Ribonucleotide incorporation, proofreading and bypass by human DNA polymerase δ
|
Kunkel TA
|
2012
|
DNA repair
|
Altered Ig Hypermutation Pattern and Frequency in Complementary Mouse Models of DNA Polymerase ζ Activity.
|
Kunkel TA
|
2012
|
Journal of immunology (Baltimore, Md. : 1950)
|
Replication infidelity via a mismatch with Watson-Crick geometry.
|
Kunkel TA
|
2011
|
Proceedings of the National Academy of Sciences of the United States of America
|
The in vitro fidelity of yeast DNA polymerase δ and polymerase ε holoenzymes during dinucleotide microsatellite DNA synthesis.
|
Kunkel TA
|
2011
|
DNA repair
|
Kinetic analysis of the unique error signature of human DNA polymerase ν
|
Kunkel TA
|
2011
|
Biochemistry
|
Mismatch repair-independent tandem repeat sequence instability resulting from ribonucleotide incorporation by DNA polymerase ε.
|
Kunkel TA
|
2011
|
DNA repair
|
Replication of ribonucleotide-containing DNA templates by yeast replicative polymerases.
|
Kunkel TA
|
2011
|
DNA repair
|
Unexpected role for Helicobacter pylori DNA polymerase I as a source of genetic variability.
|
Kunkel TA
|
2011
|
PLoS genetics
|
Refolding active human DNA polymerase nu from inclusion bodies.
|
Kunkel TA
|
2010
|
Protein Expr Purif
|
Genome-wide model for the normal eukaryotic DNA replication fork.
|
Kunkel TA
|
2010
|
Proceedings of the National Academy of Sciences of the United States of America
|
Mutator phenotypes due to DNA replication infidelity.
|
Kunkel TA
|
2010
|
Seminars in cancer biology
|
Mismatch repair-independent increase in spontaneous mutagenesis in yeast lacking non-essential subunits of DNA polymerase epsilon.
|
Kunkel TA
|
2010
|
PLoS Genet
|
Genome instability due to ribonucleotide incorporation into DNA.
|
Kunkel TA
|
2010
|
Nature chemical biology
|
Loop 1 modulates the fidelity of DNA polymerase {lambda}
|
Kunkel TA
|
2010
|
Nucleic acids research
|
Inhibition of short patch and long patch base excision repair by an oxidized abasic site.
|
Kunkel TA
|
2010
|
Biochemistry
|
Evolutionary conservation of residues in vertebrate DNA polymerase N conferring low fidelity and bypass activity.
|
Kunkel TA
|
2010
|
Nucleic acids research
|
Abundant ribonucleotide incorporation into DNA by yeast replicative polymerases.
|
Kunkel TA
|
2010
|
Proceedings of the National Academy of Sciences of the United States of America
|
Differential correction of lagging-strand replication errors made by DNA polymerases {alpha} and {delta}.
|
Kunkel TA
|
2010
|
Proceedings of the National Academy of Sciences of the United States of America
|
The interaction between DNA polymerase lambda and anticancer nucleoside analogs.
|
Kunkel TA
|
2010
|
The Journal of biological chemistry
|
The efficiency and fidelity of 8-oxo-guanine bypass by DNA polymerases delta and eta.
|
Kunkel TA
|
2009
|
Nucleic acids research
|
Low-fidelity DNA synthesis by the L979F mutator derivative of Saccharomyces cerevisiae DNA polymerase zeta.
|
Kunkel TA
|
2009
|
Nucleic acids research
|
Characterization of a natural mutator variant of human DNA polymerase lambda which promotes chromosomal instability by compromising NHEJ.
|
Kunkel TA
|
2009
|
PloS one
|
Template strand scrunching during DNA gap repair synthesis by human polymerase lambda.
|
Kunkel TA
|
2009
|
Nature structural & molecular biology
|
Low-fidelity DNA synthesis by human DNA polymerase theta.
|
Kunkel TA
|
2008
|
Nucleic acids research
|
The fidelity of DNA synthesis by eukaryotic replicative and translesion synthesis polymerases.
|
Kunkel TA
|
2008
|
Cell research
|
Tolerance for 8-oxoguanine but not thymine glycol in alignment-based gap filling of partially complementary double-strand break ends by DNA polymerase lambda in human nuclear extracts.
|
Kunkel TA
|
2008
|
Nucleic acids research
|
Characterization of a replicative DNA polymerase mutant with reduced fidelity and increased translesion synthesis capacity.
|
Kunkel TA
|
2008
|
Nucleic acids research
|
Catalytic mechanism of human DNA polymerase lambda with Mg2+ and Mn2+ from ab initio quantum mechanical/molecular mechanical studies.
|
Kunkel TA
|
2008
|
DNA repair
|
DNA polymerase epsilon: a polymerase of unusual size (and complexity).
|
Kunkel TA
|
2008
|
Prog Nucleic Acid Res Mol Biol
|
Division of labor at the eukaryotic replication fork.
|
Kunkel TA
|
2008
|
Molecular cell
|
Trace amounts of 8-oxo-dGTP in mitochondrial dNTP pools reduce DNA polymerase gamma replication fidelity.
|
Kunkel TA
|
2008
|
Nucleic acids research
|
Dividing the workload at a eukaryotic replication fork.
|
Kunkel TA
|
2008
|
Trends Cell Biol
|
Substrate-induced DNA strand misalignment during catalytic cycling by DNA polymerase lambda.
|
Kunkel TA
|
2008
|
EMBO Rep
|
Effects of accessory proteins on the bypass of a cis-syn thymine-thymine dimer by Saccharomyces cerevisiae DNA polymerase eta.
|
Kunkel TA
|
2007
|
Biochemistry
|
Mutator alleles of yeast DNA polymerase zeta.
|
Kunkel TA
|
2007
|
DNA repair
|
Inefficient proofreading and biased error rates during inaccurate DNA synthesis by a mutant derivative of Saccharomyces cerevisiae DNA polymerase delta.
|
Kunkel TA
|
2007
|
The Journal of biological chemistry
|
Yeast DNA polymerase epsilon participates in leading-strand DNA replication.
|
Kunkel TA
|
2007
|
Science
|
Role of the catalytic metal during polymerization by DNA polymerase lambda.
|
Kunkel TA
|
2007
|
DNA repair
|
Structural insight into the substrate specificity of DNA Polymerase mu.
|
Kunkel TA
|
2007
|
Nature structural & molecular biology
|
Replication of 2-hydroxyadenine-containing DNA and recognition by human MutSalpha.
|
Kunkel TA
|
2007
|
DNA repair
|
A unique error signature for human DNA polymerase nu.
|
Kunkel TA
|
2007
|
DNA repair
|
The X family portrait: structural insights into biological functions of X family polymerases.
|
Kunkel TA
|
2007
|
DNA repair
|
Regulation of B family DNA polymerase fidelity by a conserved active site residue: characterization of M644W, M644L and M644F mutants of yeast DNA polymerase epsilon.
|
Kunkel TA
|
2007
|
Nucleic acids research
|
RNA-templated DNA repair.
|
Kunkel TA
|
2007
|
Nature
|
Measuring the fidelity of translesion DNA synthesis.
|
Kunkel TA
|
2006
|
Methods in enzymology
|
Structural analysis of strand misalignment during DNA synthesis by a human DNA polymerase.
|
Kunkel TA
|
2006
|
Cell
|
Promiscuous mismatch extension by human DNA polymerase lambda.
|
Kunkel TA
|
2006
|
Nucleic acids research
|
RPA and PCNA suppress formation of large deletion errors by yeast DNA polymerase delta.
|
Kunkel TA
|
2006
|
Nucleic acids research
|
Evidence that errors made by DNA polymerase alpha are corrected by DNA polymerase delta.
|
Kunkel TA
|
2006
|
Current biology : CB
|
The fidelity of DNA synthesis by yeast DNA polymerase zeta alone and with accessory proteins.
|
Kunkel TA
|
2006
|
Nucleic acids research
|
Multiple solutions to inefficient lesion bypass by T7 DNA polymerase.
|
Kunkel TA
|
2006
|
DNA repair
|
Increased susceptibility to UV-induced skin carcinogenesis in polymerase eta-deficient mice.
|
Kunkel TA
|
2006
|
Cancer research
|
Participation of mouse DNA polymerase iota in strand-biased mutagenic bypass of UV photoproducts and suppression of skin cancer.
|
Kunkel TA
|
2006
|
Proceedings of the National Academy of Sciences of the United States of America
|
The multiple biological roles of the 3'-->5' exonuclease of Saccharomyces cerevisiae DNA polymerase delta require switching between the polymerase and exonuclease domains.
|
Kunkel TA
|
2005
|
Molecular and cellular biology
|
A lysine residue in the fingers subdomain of T7 DNA polymerase modulates the miscoding potential of 8-oxo-7,8-dihydroguanosine.
|
Kunkel TA
|
2005
|
Structure (London, England : 1993)
|
Biochemical properties of Saccharomyces cerevisiae DNA polymerase IV.
|
Kunkel TA
|
2005
|
The Journal of biological chemistry
|
A closed conformation for the Pol lambda catalytic cycle.
|
Kunkel TA
|
2005
|
Nature structural & molecular biology
|
Saccharomyces cerevisiae DNA polymerase delta: high fidelity for base substitutions but lower fidelity for single- and multi-base deletions.
|
Kunkel TA
|
2005
|
The Journal of biological chemistry
|
A gradient of template dependence defines distinct biological roles for family X polymerases in nonhomologous end joining.
|
Kunkel TA
|
2005
|
Molecular cell
|
Structure-function studies of DNA polymerase lambda.
|
Kunkel TA
|
2005
|
DNA repair
|
Pol iota is a candidate for the mouse pulmonary adenoma resistance 2 locus, a major modifier of chemically induced lung neoplasia.
|
Kunkel TA
|
2004
|
Cancer research
|
Functions of DNA polymerases.
|
Kunkel TA
|
2004
|
Adv Protein Chem
|
Enzymatic switching for efficient and accurate translesion DNA replication.
|
Kunkel TA
|
2004
|
Nucleic acids research
|
Investigating the role of the little finger domain of Y-family DNA polymerases in low fidelity synthesis and translesion replication.
|
Kunkel TA
|
2004
|
The Journal of biological chemistry
|
Efficiency, fidelity and enzymatic switching during translesion DNA synthesis.
|
Kunkel TA
|
2004
|
Cell cycle (Georgetown, Tex.)
|
Evidence for interplay among yeast replicative DNA polymerases alpha, delta and epsilon from studies of exonuclease and polymerase active site mutations.
|
Kunkel TA
|
2004
|
BMC biology
|
Preferential cis-syn thymine dimer bypass by DNA polymerase eta occurs with biased fidelity.
|
Kunkel TA
|
2004
|
Nature
|
Implication of DNA polymerase lambda in alignment-based gap filling for nonhomologous DNA end joining in human nuclear extracts.
|
Kunkel TA
|
2004
|
The Journal of biological chemistry
|
DNA replication fidelity.
|
Kunkel TA
|
2004
|
The Journal of biological chemistry
|
A structural solution for the DNA polymerase lambda-dependent repair of DNA gaps with minimal homology.
|
Kunkel TA
|
2004
|
Molecular cell
|
Structural basis for the dual coding potential of 8-oxoguanosine by a high-fidelity DNA polymerase.
|
Kunkel TA
|
2004
|
The EMBO journal
|
The base substitution fidelity of DNA polymerase beta-dependent single nucleotide base excision repair.
|
Kunkel TA
|
2003
|
The Journal of biological chemistry
|
Roles of Saccharomyces cerevisiae DNA polymerases Poleta and Polzeta in response to irradiation by simulated sunlight.
|
Kunkel TA
|
2003
|
Nucleic acids research
|
Mutations in DNA polymerase gamma cause error prone DNA synthesis in human mitochondrial disorders.
|
Kunkel TA
|
2003
|
Acta Biochim Pol
|
Cadmium is a mutagen that acts by inhibiting mismatch repair.
|
Kunkel TA
|
2003
|
Nature genetics
|
The efficiency and specificity of apurinic/apyrimidinic site bypass by human DNA polymerase eta and Sulfolobus solfataricus Dpo4.
|
Kunkel TA
|
2003
|
The Journal of biological chemistry
|
Amino acid substitutions at conserved tyrosine 52 alter fidelity and bypass efficiency of human DNA polymerase eta.
|
Kunkel TA
|
2003
|
The Journal of biological chemistry
|
Localization of the deoxyribose phosphate lyase active site in human DNA polymerase iota by controlled proteolysis.
|
Kunkel TA
|
2003
|
The Journal of biological chemistry
|
Considering the cancer consequences of altered DNA polymerase function.
|
Kunkel TA
|
2003
|
Cancer Cell
|
Unique error signature of the four-subunit yeast DNA polymerase epsilon.
|
Kunkel TA
|
2003
|
The Journal of biological chemistry
|
The frameshift infidelity of human DNA polymerase lambda. Implications for function.
|
Kunkel TA
|
2003
|
The Journal of biological chemistry
|
Functions of human DNA polymerases eta, kappa and iota suggested by their properties, including fidelity with undamaged DNA templates.
|
Kunkel TA
|
2003
|
DNA repair
|
Solution structure of the lyase domain of human DNA polymerase lambda.
|
Kunkel TA
|
2003
|
Biochemistry
|
Active site mutation in DNA polymerase gamma associated with progressive external ophthalmoplegia causes error-prone DNA synthesis.
|
Kunkel TA
|
2002
|
The Journal of biological chemistry
|
Discrimination against purine-pyrimidine mispairs in the polymerase active site of DNA polymerase I: a structural explanation.
|
Kunkel TA
|
2002
|
Proceedings of the National Academy of Sciences of the United States of America
|
Correlation of somatic hypermutation specificity and A-T base pair substitution errors by DNA polymerase eta during copying of a mouse immunoglobulin kappa light chain transgene.
|
Kunkel TA
|
2002
|
Proceedings of the National Academy of Sciences of the United States of America
|
Family growth: the eukaryotic DNA polymerase revolution.
|
Kunkel TA
|
2002
|
Cell Mol Life Sci
|
Low fidelity DNA synthesis by a y family DNA polymerase due to misalignment in the active site.
|
Kunkel TA
|
2002
|
The Journal of biological chemistry
|
DNA polymerase lambda, a novel DNA repair enzyme in human cells.
|
Kunkel TA
|
2002
|
The Journal of biological chemistry
|
Somatic mutation hotspots correlate with DNA polymerase eta error spectrum.
|
Kunkel TA
|
2001
|
Nat Immunol
|
5'-Deoxyribose phosphate lyase activity of human DNA polymerase iota in vitro.
|
Kunkel TA
|
2001
|
Science
|
Proofreading of DNA polymerase eta-dependent replication errors.
|
Kunkel TA
|
2001
|
The Journal of biological chemistry
|
Error rate and specificity of human and murine DNA polymerase eta.
|
Kunkel TA
|
2001
|
Journal of molecular biology
|
Identification of an intrinsic 5'-deoxyribose-5-phosphate lyase activity in human DNA polymerase lambda: a possible role in base excision repair.
|
Kunkel TA
|
2001
|
The Journal of biological chemistry
|
In vivo consequences of putative active site mutations in yeast DNA polymerases alpha, epsilon, delta, and zeta.
|
Kunkel TA
|
2001
|
Genetics
|
The fidelity of human DNA polymerase gamma with and without exonucleolytic proofreading and the p55 accessory subunit.
|
Kunkel TA
|
2001
|
The Journal of biological chemistry
|
Mutator effects of overproducing DNA polymerase eta (Rad30) and its catalytically inactive variant in yeast.
|
Kunkel TA
|
2001
|
Mutation research
|
The 3'-->5' exonuclease of DNA polymerase delta can substitute for the 5' flap endonuclease Rad27/Fen1 in processing Okazaki fragments and preventing genome instability.
|
Kunkel TA
|
2001
|
Proceedings of the National Academy of Sciences of the United States of America
|
Human DNA polymerase kappa: a novel DNA polymerase of unknown biological function encoded by the DINB1 gene.
|
Kunkel TA
|
2000
|
Cold Spring Harbor symposia on quantitative biology
|
Fidelity and processivity of DNA synthesis by DNA polymerase kappa, the product of the human DINB1 gene.
|
Kunkel TA
|
2000
|
The Journal of biological chemistry
|
Vertical-scanning mutagenesis of a critical tryptophan in the "minor groove binding track" of HIV-1 reverse transcriptase. Major groove DNA adducts identify specific protein interactions in the minor groove.
|
Kunkel TA
|
2000
|
The Journal of biological chemistry
|
Low fidelity DNA synthesis by human DNA polymerase-eta.
|
Kunkel TA
|
2000
|
Nature
|
Minor groove interactions at the DNA polymerase beta active site modulate single-base deletion error rates.
|
Kunkel TA
|
2000
|
The Journal of biological chemistry
|
DNA replication fidelity.
|
Kunkel TA
|
2000
|
Annual review of biochemistry
|
Residues in the alphaH and alphaI helices of the HIV-1 reverse transcriptase thumb subdomain required for the specificity of RNase H-catalyzed removal of the polypurine tract primer.
|
Kunkel TA
|
1999
|
The Journal of biological chemistry
|
Deletion errors generated during replication of CAG repeats.
|
Kunkel TA
|
1999
|
Nucleic acids research
|
Mutator phenotypes of yeast strains heterozygous for mutations in the MSH2 gene.
|
Kunkel TA
|
1999
|
Proceedings of the National Academy of Sciences of the United States of America
|
Uniquely altered DNA replication fidelity conferred by an amino acid change in the nucleotide binding pocket of human immunodeficiency virus type 1 reverse transcriptase.
|
Kunkel TA
|
1999
|
The Journal of biological chemistry
|
Base substitution specificity of DNA polymerase beta depends on interactions in the DNA minor groove.
|
Kunkel TA
|
1999
|
The Journal of biological chemistry
|
The base substitution fidelity of HIV-1 reverse transcriptase on DNA and RNA templates probed with 8-oxo-deoxyguanosine triphosphate.
|
Kunkel TA
|
1999
|
Mutation research
|
The fidelity of DNA polymerase beta during distributive and processive DNA synthesis.
|
Kunkel TA
|
1999
|
The Journal of biological chemistry
|
Side chains that influence fidelity at the polymerase active site of Escherichia coli DNA polymerase I (Klenow fragment).
|
Kunkel TA
|
1999
|
The Journal of biological chemistry
|
Effect of accessory proteins on T4 DNA polymerase replication fidelity.
|
Kunkel TA
|
1998
|
Journal of molecular biology
|
Vertical-scanning mutagenesis of a critical tryptophan in the minor groove binding track of HIV-1 reverse transcriptase. Molecular nature of polymerase-nucleic acid interactions.
|
Kunkel TA
|
1998
|
The Journal of biological chemistry
|
Correction of hypermutability, N-methyl-N'-nitro-N-nitrosoguanidine resistance, and defective DNA mismatch repair by introducing chromosome 2 into human tumor cells with mutations in MSH2 and MSH6.
|
Kunkel TA
|
1997
|
Cancer research
|
A minor groove binding track in reverse transcriptase.
|
Kunkel TA
|
1997
|
Nat Struct Biol
|
Base miscoding and strand misalignment errors by mutator Klenow polymerases with amino acid substitutions at tyrosine 766 in the O helix of the fingers subdomain.
|
Kunkel TA
|
1997
|
The Journal of biological chemistry
|
Probing structure/function relationships of HIV-1 reverse transcriptase with styrene oxide N2-guanine adducts.
|
Kunkel TA
|
1997
|
The Journal of biological chemistry
|
Role of the "helix clamp" in HIV-1 reverse transcriptase catalytic cycling as revealed by alanine-scanning mutagenesis.
|
Kunkel TA
|
1996
|
The Journal of biological chemistry
|
Base analog N6-hydroxylaminopurine mutagenesis in Escherichia coli: genetic control and molecular specificity.
|
Kunkel TA
|
1996
|
Mutation research
|
Enzyme-DNA interactions required for efficient nucleotide incorporation and discrimination in human DNA polymerase beta.
|
Kunkel TA
|
1996
|
The Journal of biological chemistry
|
A thumb subdomain mutant of the large fragment of Escherichia coli DNA polymerase I with reduced DNA binding affinity, processivity, and frameshift fidelity.
|
Kunkel TA
|
1996
|
The Journal of biological chemistry
|
Exonucleolytic proofreading during replication of repetitive DNA.
|
Kunkel TA
|
1996
|
Biochemistry
|
Reduced frameshift fidelity and processivity of HIV-1 reverse transcriptase mutants containing alanine substitutions in helix H of the thumb subdomain.
|
Kunkel TA
|
1995
|
The Journal of biological chemistry
|
Purification and properties of wild-type and exonuclease-deficient DNA polymerase II from Escherichia coli.
|
Kunkel TA
|
1995
|
The Journal of biological chemistry
|
Analyzing fidelity of DNA polymerases.
|
Kunkel TA
|
1995
|
Methods in enzymology
|
Error-prone replication of repeated DNA sequences by T7 DNA polymerase in the absence of its processivity subunit.
|
Kunkel TA
|
1994
|
Proceedings of the National Academy of Sciences of the United States of America
|
Structure/function studies of human immunodeficiency virus type 1 reverse transcriptase. Alanine scanning mutagenesis of an alpha-helix in the thumb subdomain.
|
Kunkel TA
|
1994
|
The Journal of biological chemistry
|
DNA replication fidelity with 8-oxodeoxyguanosine triphosphate.
|
Kunkel TA
|
1994
|
Biochemistry
|
A beta-like DNA polymerase from the mitochondrion of the trypanosomatid Crithidia fasciculata.
|
Kunkel TA
|
1994
|
The Journal of biological chemistry
|
Effect of reaction pH on the fidelity and processivity of exonuclease-deficient Klenow polymerase.
|
Kunkel TA
|
1993
|
The Journal of biological chemistry
|
Fidelity of DNA synthesis catalyzed by human DNA polymerase alpha and HIV-1 reverse transcriptase: effect of reaction pH.
|
Kunkel TA
|
1993
|
Nucleic acids research
|
Error-prone polymerization by HIV-1 reverse transcriptase. Contribution of template-primer misalignment, miscoding, and termination probability to mutational hot spots.
|
Kunkel TA
|
1993
|
The Journal of biological chemistry
|
Mechanism of HIV-1 reverse transcriptase. Termination of processive synthesis on a natural DNA template is influenced by the sequence of the template-primer stem.
|
Kunkel TA
|
1993
|
The Journal of biological chemistry
|
Structure/function studies of HIV-1(1) reverse transcriptase: dimerization-defective mutant L289K.
|
Kunkel TA
|
1993
|
Biochemistry
|
The effects of dNTP pool imbalances on frameshift fidelity during DNA replication.
|
Kunkel TA
|
1992
|
The Journal of biological chemistry
|
Unequal human immunodeficiency virus type 1 reverse transcriptase error rates with RNA and DNA templates.
|
Kunkel TA
|
1992
|
Proceedings of the National Academy of Sciences of the United States of America
|
Biochemical studies on the reverse transcriptase and RNase H activities from human immunodeficiency virus strains resistant to 3'-azido-3'-deoxythymidine.
|
Kunkel TA
|
1992
|
The Journal of biological chemistry
|
DNA polymerase fidelity and the polymerase chain reaction.
|
Kunkel TA
|
1991
|
PCR Methods Appl
|
Heteroduplex repair in extracts of human HeLa cells.
|
Kunkel TA
|
1991
|
The Journal of biological chemistry
|
Eukaryotic DNA polymerase amino acid sequence required for 3'----5' exonuclease activity.
|
Kunkel TA
|
1991
|
Proceedings of the National Academy of Sciences of the United States of America
|
The fidelity of DNA synthesis by the catalytic subunit of yeast DNA polymerase alpha alone and with accessory proteins.
|
Kunkel TA
|
1991
|
Mutation research
|
Exonucleolytic proofreading of leading and lagging strand DNA replication errors.
|
Kunkel TA
|
1991
|
Proceedings of the National Academy of Sciences of the United States of America
|
Fidelity of mammalian DNA replication and replicative DNA polymerases.
|
Kunkel TA
|
1991
|
Biochemistry
|
Frameshift errors initiated by nucleotide misincorporation.
|
Kunkel TA
|
1990
|
Proceedings of the National Academy of Sciences of the United States of America
|
The fidelity of DNA synthesis catalyzed by derivatives of Escherichia coli DNA polymerase I.
|
Kunkel TA
|
1990
|
The Journal of biological chemistry
|
Purification and characterization of DNA polymerase II from the yeast Saccharomyces cerevisiae. Identification of the catalytic core and a possible holoenzyme form of the enzyme.
|
Kunkel TA
|
1990
|
The Journal of biological chemistry
|
Fidelity of animal cell DNA polymerases alpha and delta and of a human DNA replication complex.
|
Kunkel TA
|
1990
|
Basic life sciences
|
High fidelity DNA synthesis by the Thermus aquaticus DNA polymerase.
|
Kunkel TA
|
1990
|
Nucleic acids research
|
Fidelity of two retroviral reverse transcriptases during DNA-dependent DNA synthesis in vitro.
|
Kunkel TA
|
1989
|
Molecular and cellular biology
|
Exonucleolytic proofreading by a mammalian DNA polymerase.
|
Kunkel TA
|
1989
|
Biochemistry
|
The use of native T7 DNA polymerase for site-directed mutagenesis.
|
Kunkel TA
|
1989
|
Nucleic acids research
|
Fidelity of DNA polymerase I and the DNA polymerase I-DNA primase complex from Saccharomyces cerevisiae.
|
Kunkel TA
|
1989
|
Molecular and cellular biology
|
Specificity and mechanism of error-prone replication by human immunodeficiency virus-1 reverse transcriptase.
|
Kunkel TA
|
1989
|
The Journal of biological chemistry
|
Kinetic analysis of base substitution mutagenesis by transient misalignment of DNA and by miscoding.
|
Kunkel TA
|
1989
|
The Journal of biological chemistry
|
Exonucleolytic proofreading.
|
Kunkel TA
|
1988
|
Cell
|
Exonucleolytic proofreading enhances the fidelity of DNA synthesis by chick embryo DNA polymerase-gamma.
|
Kunkel TA
|
1988
|
The Journal of biological chemistry
|
Fidelity of a human cell DNA replication complex.
|
Kunkel TA
|
1988
|
Proceedings of the National Academy of Sciences of the United States of America
|
The accuracy of reverse transcriptase from HIV-1.
|
Kunkel TA
|
1988
|
Science (New York, N.Y.)
|
Fidelity of DNA synthesis by the Thermus aquaticus DNA polymerase.
|
Kunkel TA
|
1988
|
Biochemistry
|
Purification and characterization of bacteriophage N4-induced DNA polymerase.
|
Kunkel TA
|
1988
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The Journal of biological chemistry
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Base substitution mutagenesis by terminal transferase: its role in somatic mutagenesis.
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Kunkel TA
|
1987
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Mutation research
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Exonucleolytic proofreading by calf thymus DNA polymerase delta.
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Kunkel TA
|
1987
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Proceedings of the National Academy of Sciences of the United States of America
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On the fidelity of DNA synthesis. Pyrophosphate-induced misincorporation allows detection of two proofreading mechanisms.
|
Kunkel TA
|
1986
|
The Journal of biological chemistry
|
Rearrangements of DNA mediated by terminal transferase.
|
Kunkel TA
|
1986
|
Proceedings of the National Academy of Sciences of the United States of America
|
Mutagenesis in vitro by DNA polymerases alpha, beta and gamma.
|
Kunkel TA
|
1986
|
Progress in clinical and biological research
|
Frameshift mutagenesis by eucaryotic DNA polymerases in vitro.
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Kunkel TA
|
1986
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The Journal of biological chemistry
|
The base substitution fidelity of eucaryotic DNA polymerases. Mispairing frequencies, site preferences, insertion preferences, and base substitution by dislocation.
|
Kunkel TA
|
1986
|
The Journal of biological chemistry
|
The mutational specificity of DNA polymerase-beta during in vitro DNA synthesis. Production of frameshift, base substitution, and deletion mutations.
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Kunkel TA
|
1985
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The Journal of biological chemistry
|
The mutational specificity of DNA polymerases-alpha and -gamma during in vitro DNA synthesis.
|
Kunkel TA
|
1985
|
The Journal of biological chemistry
|
On the fidelity of DNA replication. The accuracy of T4 DNA polymerases in copying phi X174 DNA in vitro.
|
Kunkel TA
|
1984
|
The Journal of biological chemistry
|
Infidelity of DNA synthesis associated with bypass of apurinic sites.
|
Kunkel TA
|
1983
|
Proceedings of the National Academy of Sciences of the United States of America
|
Depurination-induced infidelity of deoxyribonucleic acid synthesis with purified deoxyribonucleic acid replication proteins in vitro.
|
Kunkel TA
|
1983
|
Biochemistry
|
The mutagenic effect of deoxynucleotide substrate imbalances during DNA synthesis with mammalian DNA polymerases.
|
Kunkel TA
|
1982
|
Mutation research
|
Depurination of DNA as a possible mutagenic pathway for cells.
|
Kunkel TA
|
1982
|
Basic life sciences
|
On the fidelity of DNA replication. Effect of the next nucleotide on proofreading.
|
Kunkel TA
|
1981
|
The Journal of biological chemistry
|
Fidelity of mammalian DNA polymerases.
|
Kunkel TA
|
1981
|
Science
|
Deoxynucleoside [1-thio]triphosphates prevent proofreading during in vitro DNA synthesis.
|
Kunkel TA
|
1981
|
Proceedings of the National Academy of Sciences of the United States of America
|
On the fidelity of DNA replication. The accuracy of Escherichia coli DNA polymerase I in copying natural DNA in vitro.
|
Kunkel TA
|
1980
|
The Journal of biological chemistry
|
Distinctive properties of mammalian DNA polymerases.
|
Kunkel TA
|
1979
|
Biochimica et biophysica acta
|
On the fidelity of DNA replication. Effect of divalent metal ion activators and deoxyrionucleoside triphosphate pools on in vitro mutagenesis.
|
Kunkel TA
|
1979
|
The Journal of biological chemistry
|
Mutagenesis in vitro by DNA polymerase from an RNA tumour virus.
|
Kunkel TA
|
1979
|
Nature
|
Single-strand binding protein enhances fidelity of DNA synthesis in vitro.
|
Kunkel TA
|
1979
|
Proceedings of the National Academy of Sciences of the United States of America
|
Purification and properties of DNA polymerase-beta from guinea pig liver.
|
Kunkel TA
|
1978
|
Biochimica et biophysica acta
|
Novikoff hepatoma deoxyribonucleic acid polymerase. Sensitivity of the beta-polymerase to sulfhydryl blocking agents.
|
Kunkel TA
|
1976
|
Nucleic acids research
|
Isolation and purification of mediators of cell proliferation.
|
Kunkel TA
|
1975
|
Archives of surgery (Chicago, Ill. : 1960)
|