RB69
From
Bacteriophage RB69
Welcome to the Polymerase Page
This page presents all the information in Polbase for RB69.
Mutants:At the top of the page you'll find a map of all positions of known mutants. Text links to mutants and digestion products are listed in the Mutants section.
Structures/Sequence:If available, a representative structure is displayed at the upper right. All known structures are listed in the Structures section.
External links:Polbase polymerases are linked to UniProt and Genbank where possible. The UniProt search link directs you to a pre-constructed UniProt search containing relevant terms.
References:All references that refer to this Polymerase are listed with their topics and paper's title in the References table.
Results:All the results for this polymerase can be examined by following the "Results" link at the bottom of the page.
Help icons:
The symbol in the upper-right corner of the page
links to this help text. The question mark icon is used everywhere to indicate that help is available.
RB69
is a family B enzyme
from
Bacteriophage RB69.
Selected Properties for RB69: |
3'-5' exo activity | 5'-3' exo activity | Frameshift Rate | Substitution Rate | General Error Rate |
|---|---|---|---|---|---|
| Yes (1) | no data | no data | no data | no data |
- References (67)
- Structures (15)
- Sequences (1)
- Mutants (51)...
- Formulations (0)
- Polymerase Lots (0)
- External links
| Year | Authors | Title | Results by property |
|---|---|---|---|
| 2015 | Hariyanto Darmawan, Melissa Harrison, Linda J Reha-Krantz | DNA polymerase 3'→5' exonuclease acti... | |
| 2013 | Shuangluo Xia, Marcus Wood, Michael J Bradley, Enrique M De La Cruz, William H Konigsberg | Alteration in the cavity size adjacen... | |
| 2012 | Shuangluo Xia, Jeff W Beckman, Jianhong Wang, William H Konigsberg | Using a Fluorescent Cytosine Analogue... | |
| 2012 | Shuangluo Xia, Soo Hyun Eom, William H Konigsberg, Jianhong Wang | Structural Basis for Differential Ins... | |
| 2012 | Shuangluo Xia, Soo Hyun Eom, William H Konigsberg, Jianhong Wang | Bidendate and tridendate metal-ion co... | |
| 2012 | Shuangluo Xia, Ashwani Kumar Vashishtha, David Bulkley, Soo Hyun Eom, Jianhong Wang, William H Konigsberg | Contribution of Partial Charge Intera... | |
| 2011 | M Hogg, AE Sauer-Eriksson, Erik Johansson | Promiscuous DNA synthesis by human DN... | |
| 2011 | Michael Wang, Shuangluo Xia, Gregor Blaha, Thomas A Steitz, William H Konigsberg, Jianhong Wang | Insights into Base Selectivity from t... | |
| 2011 | Shuangluo Xia, Michael Wang, Gregor Blaha, William H Konigsberg, Jianhong Wang | Structural Insights into Complete Met... | |
| 2011 | Shuangluo Xia, William H Konigsberg, Jianhong Wang | Hydrogen-bonding capability of a temp... | |
| 2011 | Shuangluo Xia, Michael Wang, Harold R Lee, Arjun Sinha, Gregor Blaha, Thomas David Christian, Jianhong Wang, William H Konigsberg | Variation in Mutation Rates Caused by... | |
| 2010 | Vasiliy M Petrov, Swarnamala Ratnayaka, Jim D Karam | Genetic insertions and diversificatio... | |
| 2010 | Kei-ichi Takata, Mercedes E Arana, Masayuki Seki, Thomas A Kunkel, Richard D Wood | Evolutionary conservation of residues... | |
| 2010 | Anna Trzemecka, Agata Jacewicz, Geraldine T Carver, John W Drake, Anna Bebenek | Reversal of a mutator activity by a n... | |
| 2010 | Linda J Reha-Krantz | DNA polymerase proofreading: Multiple... | |
| 2010 | Jeff W Beckman, Michael Wang, Gregor Blaha, Jianhong Wang, William H Konigsberg | Substitution of Ala for Tyr567 in RB6... | |
| 2010 | Jeff W Beckman, Michael Wang, Gregor Blaha, Jianhong Wang, William H Konigsberg | Substitution of Ala for Tyr567 in RB6... | |
| 2010 | Matthew Hogg, Jean Rudnicki, John Midkiff, Linda J Reha-Krantz, Sylvie Doublié, Susan S Wallace | Kinetics of mismatch formation opposi... | |
| 2009 | Haijiang Zhang, Jeff W Beckman, Jianhong Wang, William H Konigsberg | RB69 DNA polymerase mutants with expa... | |
| 2009 | Michael Wang, Harold R Lee, William H Konigsberg | Effect of A and B metal ion site occu... | |
| 2009 | Harold R Lee, Michael Wang, William H Konigsberg | The reopening rate of the fingers dom... | |
| 2009 | Egor P Tchesnokov, Aleksandr Obikhod, Raymond F Schinazi, Matthias Götte | Engineering of a chimeric RB69 DNA po... | |
| 2009 | Anna Trzemecka, Danuta Płochocka, Anna Bebenek | Different behaviors in vivo of mutati... | Kd,All properties |
| 2008 | Usharani Subuddhi, Matthew Hogg, Linda J Reha-Krantz | Use of 2-aminopurine fluorescence to ... | |
| 2008 | Xuejun Zhong, Lars C Pedersen, Thomas A Kunkel | Characterization of a replicative DNA... | |
| 2007 | Haijiang Zhang, W Cao, E Zakharova, William H Konigsberg, E M De La Cruz | Fluorescence of 2-aminopurine reveals... | |
| 2007 | Pierre Aller, Mark A Rould, Matthew Hogg, Susan S Wallace, Sylvie Doublié | A structural rationale for stalling o... | |
| 2007 | Karl E Zahn, Hassan Belrhali, Susan S Wallace, Sylvie Doublié | Caught bending the A-rule: crystal st... | |
| 2007 | Christian Castro, Eric D Smidansky, Kenneth R Maksimchuk, Jamie J Arnold, Victoria S Korneeva, Matthias Götte, William H Konigsberg, Craig E Cameron | Two proton transfers in the transitio... | |
| 2007 | Agata Jacewicz, Karolina Makiela, Andrzej Kierzek, John W Drake, Anna Bebenek | The roles of Tyr391 and Tyr619 in RB6... | |
| 2007 | Matthew Hogg, Pierre Aller, William H Konigsberg, Susan S Wallace, Sylvie Doublié | Structural and biochemical investigat... | 3-5' exo,All properties |
| 2007 | Dina Tleugabulova, Linda J Reha-Krantz | Probing DNA polymerase-DNA interactio... | |
| 2006 | Vasiliy M Petrov, James M Nolan, Claire Bertrand, Dawn Levy, Carine Desplats, H M Krisch, Jim D Karam | Plasticity of the gene functions for ... | |
| 2006 | Siyang Sun, Linda Geng, Yousif Shamoo | Structure and enzymatic properties of... | Cloned or native,Full length or truncated,Processivity,Kd,All properties |
| 2006 | Haijiang Zhang, Chanu Rhee, Anna Bebenek, John W Drake, Jianhong Wang, William H Konigsberg | The L561A substitution in the nascent... | Kd,kcat,All properties |
| 2006 | Matthew Hogg, Wendy Cooper, Linda J Reha-Krantz, Susan S Wallace | Kinetics of error generation in homol... | |
| 2005 | Guangwei Yang, Jianhong Wang, William H Konigsberg | Base selectivity is impaired by mutan... | |
| 2005 | John W Drake, Anna Bebenek, Grace E Kissling, Shyamal Peddada | Clusters of mutations from transient ... | |
| 2005 | Anna Bebenek, Geraldine T Carver, Farid A Kadyrov, Grace E Kissling, John W Drake | Processivity clamp gp45 and ssDNA-bin... | |
| 2005 | Matthew Hogg, Susan S Wallace, Sylvie Doublié | Bumps in the road: how replicative DN... | |
| 2004 | Eva Freisinger, Arthur P Grollman, Holly Miller, Caroline Kisker | Lesion (in)tolerance reveals insights... | |
| 2004 | E Zakharova, Jianhong Wang, William H Konigsberg | The activity of selected RB69 DNA pol... | |
| 2004 | Matthew Hogg, Susan S Wallace, Sylvie Doublié | Crystallographic snapshots of a repli... | |
| 2004 | C X Wang, E Zakharova, Jinming Li, Catherine M Joyce, Jianhong Wang, William H Konigsberg | Pre-steady-state kinetics of RB69 DNA... | kcat,All properties |
| 2004 | Vasiliy M Petrov, Jim D Karam | Diversity of structure and function o... | |
| 2004 | Andrew F Gardner, Catherine M Joyce, William E Jack | Comparative kinetics of nucleotide an... | |
| 2003 | William A Beard, Samuel H Wilson | Structural insights into the origins ... | |
| 2003 | Siyang Sun, Yousif Shamoo | Biochemical characterization of inter... | |
| 2002 | Guangwei Yang, Matthew Franklin, Jinming Li, T C Lin, William H Konigsberg | Correlation of the kinetics of finger... | |
| 2002 | David Jeruzalmi, Mike E O'Donnell, John Kuriyan | Clamp loaders and sliding clamps. | |
| 2002 | Vasiliy M Petrov, Jim D Karam | RNA determinants of translational ope... | |
| 2002 | Anna Bebenek, Geraldine T Carver, Holly Kloos Dressman, Farid A Kadyrov, Joseph K Haseman, Vasiliy M Petrov, William H Konigsberg, Jim D Karam, John W Drake | Dissecting the fidelity of bacterioph... | |
| 2002 | Vasiliy M Petrov, San-San Ng, Jim D Karam | Protein determinants of RNA binding b... | |
| 2001 | M C Franklin, Jianhong Wang, Thomas A Steitz | Structure of the replicating complex ... | |
| 2001 | Anna Bebenek, Holly Kloos Dressman, Geraldine T Carver, S Ng , Vasiliy M Petrov, Guangwei Yang, William H Konigsberg, Jim D Karam, John W Drake | Interacting fidelity defects in the r... | |
| 1999 | Guangwei Yang, T Lin, J Karam, William H Konigsberg | Steady-state kinetic characterization... | |
| 1999 | Thomas A Steitz | DNA polymerases: structural diversity... | |
| 1999 | J M Stattel, George E Wright | Sensitivity of bacteriophage RB69 DNA... | |
| 1998 | L A Smith, John W Drake | Aspects of the ultraviolet photobiolo... | |
| 1998 | L S Yeh, Tien Hsu, Jim D Karam | Divergence of a DNA replication gene ... | |
| 1998 | Nancy G Nossal | A new look at old mutants of T4 DNA p... | |
| 1998 | J Saturno, José María Lázaro, Luis Blanco, Margarita Salas | Role of the first aspartate residue o... | |
| 1997 | Holly Kloos Dressman, C C Wang, Jim D Karam, John W Drake | Retention of replication fidelity by ... | |
| 1997 | C C Wang, A Pavlov, Jim D Karam | Evolution of RNA-binding specificity ... | |
| 1997 | Jianhong Wang, A K Sattar, C C Wang, Jim D Karam, William H Konigsberg, Thomas A Steitz | Crystal structure of a pol alpha fami... | |
| 1995 | C C Wang, L S Yeh, Jim D Karam | Modular organization of T4 DNA polyme... | |
| 1990 | C Tuerk, S Eddy, D Parma, L Gold | Autogenous translational operator rec... |
Protein sequence:
Protein information: Uniprot Q38087 search for RB69 at UniProt
Sequence information: NCBI nucleotides European nucleotide archive